SCHEMBL3322365

SCHEMBL3322365

COc1ccc(NC(C)O)c([N+](=O)[O-])c1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.56
RAB9A P51151 6/20 0.56
NPC1 O15118 5/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
MAPK1 P28482 2/20 0.56
AKR1C3 P42330 3/20 0.55
AKR1C2 P52895 3/20 0.55
ALDH1A1 P00352 2/20 0.55
LMNA P02545 2/20 0.55
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
AKR1B10 O60218 1/20 0.52
AKR1B1 P15121 1/20 0.52
AKR1C4 P17516 1/20 0.52
AKR1C1 Q04828 1/20 0.52
THRB P10828 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C9 P11712 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7362765 0.88 HCAR3 (0.58) MAPTRAB9ANPC1SMN1; SMN2MAPK1
SCHEMBL14734344 0.85 MAPT (0.56) MAPTRAB9ANPC1SMN1; SMN2MAPK1
SCHEMBL3819214 0.80 HCAR3 (0.45) MAPTRAB9ANPC1SMN1; SMN2MAPK1
SCHEMBL129286 0.80 HCAR3 (0.52) MAPTSMN1; SMN2MAPK1ALDH1A1MEN1
SCHEMBL4626839 0.80 TSHR (0.53) RAB9ANPC1SMN1; SMN2ALDH1A1CYP3A4
SCHEMBL1888218 0.80 HCAR3 (0.54) MAPTALDH1A1MEN1KMT2A
SCHEMBL6156984 0.80 CRHBP (0.65) MAPTSMN1; SMN2MAPK1ALDH1A1MEN1
SCHEMBL5158786 0.80 MAPT (0.45) MAPTRAB9ANPC1SMN1; SMN2MAPK1
SCHEMBL7071559 0.80 LMNA (0.76) MAPTRAB9ANPC1SMN1; SMN2MAPK1
SCHEMBL430629 0.80 MAPT (0.59) MAPTRAB9ANPC1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9993413-B2 Keratin fibre dyeing composition BEAUTY & BUSINESS S.P.A. (IT) 2018-06-12 US claimed
US-20170258695-A1 KERATIN FIBRE DYEING COMPOSITION BEAUTY & BUSINESS S.P.A. (IT) 2017-09-14 US claimed
WO-2008099332-A1 MULTISTEP HAIR COLOR REVITALIZING KIT AND ASSOCIATED METHODS THE PROCTER & GAMBLE COMPANY (US) 2008-08-21 WO claimed
US-20080189876-A1 Multistep hair color revitalizing kit and associated methods PROCTER & GAMBLE COMPANY, THE 2008-08-14 US claimed
US-4311478-A HAIR DYES L'OREAL (FR) 1982-01-19 US claimed
US-12583876-B2 Branched organosilicon compound, method of preparing same, and related compositions DOW SILICONES CORPORATION (US) 2026-03-24 US disclosed
EP-3493878-B1 COSMETIC COMPOSITION COMPRISING CURED SILICONE MATERIALS DOW SILICONES CORP (US) 2025-10-08 EP disclosed
US-12398270-B2 Acrylate-functional branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-08-26 US disclosed
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-07-29 US disclosed
US-12338259-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith DOW SILICONES CORPORATION (US) 2025-06-24 US disclosed
US-12337052-B2 Hair treatment method that increases the bond density of damaged hair BEAUTY & BUSINESS S.P.A. (IT) 2025-06-24 US disclosed
EP-4548908-A1 PERMANENT OXIDATIVE HAIR-COLOURING COMPOSITIONS Beauty & Business SpA (IT) 2025-05-07 EP disclosed
WO-2001007009-A1 LYSINE OXIDASE LINKAGE OF AGENTS TO TISSUE PERICOR SCIENCE, INC. (US) 2001-02-01 WO disclosed
WO-2001006829-A2 LINKAGE OF AGENTS TO TISSUE PERICOR SCIENCE, INC. (US) 2001-02-01 WO disclosed
EP-0633915-B1 A METHOD AND LIQUID COMPOSITION FOR THE PRODUCTION OF INDELIBLE SCRIPT ON A PAPER SUBSTRATE SEGALLA GABRIELE (IT) 1998-02-04 EP disclosed
US-5637354-A USING OXIDATIVE FIBER REACTIVE DYE SEGALLA GABRIELE (IT) 1997-06-10 US disclosed
EP-0633915-A1 A METHOD AND LIQUID COMPOSITION FOR THE PRODUCTION OF INDELIBLE SCRIPT ON A PAPER SUBSTRATE SEGALLA, Gabriele (IT) 1995-01-18 EP disclosed
WO-1993020160-A1 A METHOD AND LIQUID COMPOSITION FOR THE PRODUCTION OF INDELIBLE SCRIPT ON A PAPER SUBSTRATE SEGALLA GABRIELE (IT) 1993-10-14 WO disclosed
US-4445521-A ANIONIC AND CATIONIC POLYMER COMBINATION L'OREAL (FR) 1984-05-01 US disclosed
US-4311478-A HAIR DYES L'OREAL (FR) 1982-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583876-B2 Branched organosilicon compound, method of preparing same, and related compositions OXSR1, BRS3, NPSR1 MAPT 4513/4885RAB9A 2155/4885NPC1 1690/4885
US-12338259-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith OXSR1, BRS3, ORC3 MAPT 4390/4885RAB9A 2417/4885NPC1 4227/4885
US-12371535-B2 Branched organosilicon compound, method of preparing same, and copolymer formed therewith OXSR1, BRS3, OXER1 MAPT 4188/4885RAB9A 3538/4885NPC1 4186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.