Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 13/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.54 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338352 | 1.00 | GRIA4 (0.54) | GRIA4GRIA2GRIA1GRIA3SCN5A | |
| SCHEMBL8164711 | 0.88 | GRIA4 (0.67) | GRIA4GRIA2GRIA1GRIA3SCN5A | |
| SCHEMBL3828607 | 0.88 | GRIA4 (0.67) | GRIA4GRIA2GRIA1GRIA3SCN5A | |
| SCHEMBL5794639 | 0.78 | GRIA4 (0.67) | GRIA4GRIA2GRIA1GRIA3 | |
| SCHEMBL30418797 | 0.76 | GRM5 (0.53) | MAPTHPGD | |
| SCHEMBL4373092 | 0.74 | GRIA4 (0.50) | GRIA4GRIA2GRIA1GRIA3 | |
| SCHEMBL28577777 | 0.72 | EGFR (0.52) | MAPTGAAHPGD | |
| SCHEMBL5878509 | 0.71 | GRIA4 (0.80) | GRIA4GRIA2GRIA1GRIA3 | |
| SCHEMBL2134262 | 0.71 | GRIA4 (1.00) | GRIA4GRIA2GRIA1GRIA3 | |
| SCHEMBL959005 | 0.71 | GRIA4 (1.00) | GRIA4GRIA2GRIA1GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097652-B2 | AMPA receptor potentiators | ELI LILLY AND COMPANY (US) | 2012-01-17 | — | — | US | disclosed |
| US-20100010090-A1 | AMPA RECEPTOR POTENTIATORS | ELI LILLY AND COMPANY | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010090-A1 | AMPA RECEPTOR POTENTIATORS | GRIN1, GRIK2, GRIK1 | GRIA4 18/4885GRIA2 14/4885GRIA1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.