SCHEMBL338486

SCHEMBL338486

O=S(=O)(O)c1ccc(-c2ccnc3c2ccc2c(-c4ccc(S(=O)(=O)O)cc4)ccnc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
IKBKB O14920 8/20 0.43
CHUK O15111 8/20 0.43
TOP2A P11388 3/20 0.43
NEK1 Q96PY6 3/20 0.42
GLO1 Q04760 1/20 0.39
ENPP2 Q13822 1/20 0.39
TSHR P16473 1/20 0.38
NT5E P21589 1/20 0.38
PIK3C3 Q8NEB9 1/20 0.38
ROCK1 Q13464 1/20 0.37
AURKB Q96GD4 1/20 0.37
AURKAIP1 Q9NWT8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16681458 0.98 LMNA (0.45) LMNAALDH1A1KDM4EMAPTHTT
SCHEMBL12131292 0.94 TOP2A (0.46) LMNAALDH1A1KDM4EMAPTHTT
SCHEMBL14163898 0.92 TDP1 (0.58) LMNAALDH1A1KDM4EMAPTHTT
SCHEMBL29265676 0.92 TDP1 (0.41) LMNAALDH1A1KDM4EMAPTHTT
SCHEMBL20725221 0.89 NR1H2 (0.49) LMNAALDH1A1KDM4EMAPTHTT
SCHEMBL13789658 0.87 KDM4E (0.38) LMNAALDH1A1KDM4EMAPTHTT
SCHEMBL13286824 0.84 PTPN11 (0.40) LMNAALDH1A1KDM4EMAPTHTT
SCHEMBL1502442 0.83 IKBKB (0.43) IKBKBCHUKTOP2ANEK1GLO1
SCHEMBL29432921 0.83 IKBKB (0.43) IKBKBCHUKTOP2ANEK1GLO1
Water SCHEMBL1502441 0.81 IKBKB (0.42) IKBKBCHUKTOP2ANEK1GLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4385499-A1 A METHOD TO ENABLE NANOPARTICLES STORED WITH A SPECIFIC TYPE OF ASSEMBLY TO MAINTAIN THIS TYPE OF ASSEMBLY UPON RECONSTITUTION Nanobacterie (FR) 2024-06-19 EP disclosed
US-20240165234-A1 METHOD TO ENABLE NANOPARTICLES STORED WITH A SPECIFIC TYPE OF ASSEMBLY TO MAINTAIN THIS TYPE OF ASSEMBLY UPON RECONSTITUTION NANOBACTERIE (FR) 2024-05-23 US disclosed
EP-4371574-A1 IRON OXIDE NANOPARTICLES COMPRISING TWO CENTERS OF ACTIVITIES OR FREE RADICAL CAPTURE/PRODUCTION FOR AN ENHANCED ACTIVITY Nanobacterie (FR) 2024-05-22 EP disclosed
EP-4371575-A1 COMBINING SPATIAL AND TEMPORAL SEQUENCES OF IRRADIATION USING A SPECIFIC NANO-SYSTEM FOR AN IMPROVED TREATMENT OF DISEASES SUCH AS CANCER Nanobacterie (FR) 2024-05-22 EP disclosed
US-20240156745-A1 IRON OXIDE NANOPARTICLES COMPRISING TWO CENTERS OF ACTIVITIES OR FREE RADICAL CAPTURE/PRODUCTION FOR AN ENHANCED ACTIVITY AND COMBINING SPATIAL AND TEMPORAL SEQUENCES OF IRRADIATION USING THE NANOPARTICLES FOR AN IMPROVED TREATMENT OF DISEASES NANOBACTERIE (FR) 2024-05-16 US disclosed
WO-2023144545-A1 SACCHARIDE SENSING SYSTEMS Carbometrics Limited (GB) 2023-08-03 WO disclosed
US-10993905-B2 Cosmetic compositions comprising magnetosomes and uses thereof NATURA BISSÉ INTERNATIONAL S.A. (ES) 2021-05-04 US disclosed
US-10974059-B2 Treatment of cancer or tumors induced by the release of heat generated by various chains of magnetosomes extracted from magnetotactic bacteria and submitted to an alternating magnetic field NANOBACTERIE (FR) 2021-04-13 US disclosed
US-20190201704-A1 TREATMENT OF CANCER OR TUMORS INDUCED BY THE RELEASE OF HEAT GENERATED BY VARIOUS CHAINS OF MAGNETOSOMES EXTRACTED FROM MAGNETOTACTIC BACTERIA AND SUBMITTED TO AN ALTERNATING MAGNETIC FIELD NANOBACTERIE (FR) 2019-07-04 US disclosed
US-10252073-B2 Treatment of cancer or tumor induced by the release of heat generated by various chains of magnetosomes extracted from magnetotactic bacteria and submitted to an alternating magnetic field NANOBACTERIE (FR) 2019-04-09 US disclosed
US-20080096028-A1 Light-Emitting Electrochemical Cell KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2008-04-24 US disclosed
US-20080057533-A1 Array for rapid detection of a microorganism KIMBERLY-CLARK WORLDWIDE, INC. 2008-03-06 US disclosed
US-20080057532-A1 Method for detecting Candida on skin KIMBERLY-CLARK WORLDWIDE, INC. 2008-03-06 US disclosed
EP-1771528-A1 LIGHT-EMITTING ELECTROCHEMICAL CELL Koninklijke Philips Electronics N.V. (NL) 2007-04-11 EP disclosed
WO-2007011696-A2 COMPOSITIONS AND METHODS FOR COUPLING A PLURALITY OF COMPOUNDS TO A SCAFFOLD THE SCRIPPS RESEARCH INSTITUTE (US) 2007-01-25 WO disclosed
US-20070020620-A1 Compositions and methods for coupling a plurality of compounds to a scaffold NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-01-25 US disclosed
WO-2006011090-A1 LIGHT-EMITTING ELECTROCHEMICAL CELL KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2006-02-02 WO disclosed
JP-2004006410-A NONAQUEOUS SECONDARY BATTERY UBE IND LTD 2004-01-08 JP disclosed
US-4966784-A FOR CALCIUM COMPOUNDS; WATER SOLUBLE INDICATOR, POROUS SPREADING LAYER CONTAINING ACID, NONMIGRATING FUJI PHOTO FILM CO., LTD. (JP) 1990-10-30 US disclosed
US-4871679-A CONTROLLED MIGRATION OF INDICATOR TO SPREADING LAYER BY SPREADING ACTION CONTROLLER FUJI PHOTO FILM CO., LTD. (JP) 1989-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080096028-A1 Light-Emitting Electrochemical Cell PPOX, CD79B, TPP2 LMNA 4603/4885ALDH1A1 1981/4885KDM4E 3901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.