Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.57 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31426435 | 0.84 | MBTD1 (0.52) | MBTD1L3MBTL3MEN1KMT2AGPR183 | |
| SCHEMBL26618202 | 0.84 | MBTD1 (0.52) | MBTD1L3MBTL3MEN1KMT2AGPR183 | |
| SCHEMBL263317 | 0.82 | MBTD1 (0.73) | MBTD1L3MBTL3MEN1KMT2AALDH1A1 | |
| SCHEMBL3384758 | 0.82 | MBTD1 (0.68) | MBTD1L3MBTL3MEN1KMT2AGPR183 | |
| SCHEMBL31689628 | 0.81 | MBTD1 (0.71) | MBTD1L3MBTL3MEN1KMT2AALDH1A1 | |
| SCHEMBL265068 | 0.81 | MBTD1 (0.71) | MBTD1L3MBTL3MEN1KMT2AALDH1A1 | |
| SCHEMBL3391959 | 0.81 | MBTD1 (0.71) | MBTD1L3MBTL3MEN1KMT2AALDH1A1 | |
| SCHEMBL16015073 | 0.81 | GLA (0.51) | GPR183ALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL3387440 | 0.80 | MBTD1 (0.70) | MBTD1L3MBTL3MEN1KMT2AGPR183 | |
| SCHEMBL295085 | 0.80 | MBTD1 (0.61) | MBTD1L3MBTL3MEN1KMT2AGPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010052448-A2 | FUSED PYRAZINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-05-14 | — | — | WO | disclosed |