Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26618202 | 1.00 | MBTD1 (0.52) | MBTD1L3MBTL3MEN1KMT2AGPR183 | |
| SCHEMBL3386199 | 0.84 | MBTD1 (0.57) | MBTD1L3MBTL3MEN1KMT2AGPR183 | |
| SCHEMBL17841225 | 0.81 | PKM (0.58) | ALDH1A1SMN1; SMN2KIF18ALMNATSHR | |
| SCHEMBL15765139 | 0.80 | MMP2 (0.49) | GPR183MMP2ALDH1A1LMNATSHR | |
| SCHEMBL18977620 | 0.79 | CYP2C9 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL3384758 | 0.78 | MBTD1 (0.68) | MBTD1L3MBTL3MEN1KMT2AGPR183 | |
| SCHEMBL28469863 | 0.78 | MBTD1 (0.56) | MBTD1L3MBTL3MEN1KMT2AGPR183 | |
| SCHEMBL263317 | 0.78 | MBTD1 (0.73) | MBTD1L3MBTL3MEN1KMT2ASIRT2 | |
| SCHEMBL31426410 | 0.77 | CA12 (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2KIF18A | |
| SCHEMBL20791554 | 0.77 | MAPT (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451951-A | Compounds for inhibition of KIF18A | 沃拉斯查疗法公司 | 2025-02-14 | — | — | CN | disclosed |