Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 8/20 | 0.54 |
| ▸ | SYK | P43405 | 2/20 | 0.54 |
| ▸ | PTK2 | Q05397 | 9/20 | 0.51 |
| ▸ | STK17A | Q9UEE5 | 4/20 | 0.49 |
| ▸ | STK17B | O94768 | 3/20 | 0.49 |
| ▸ | BCL6 | P41182 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 2/20 | 0.48 |
| ▸ | ULK1 | O75385 | 1/20 | 0.47 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386234 | 0.88 | SYK (0.59) | PTK2BSYKPTK2BCL6ULK1 | |
| SCHEMBL13431931 | 0.85 | TBK1 (0.67) | STK17AULK1ULK2 | |
| SCHEMBL5493564 | 0.84 | PTK2B (0.75) | PTK2BPTK2STK17ACHEK1FLT3 | |
| SCHEMBL3383778 | 0.82 | STK17A (0.53) | STK17ASTK17BCHEK1FLT3ULK1 | |
| SCHEMBL3389585 | 0.80 | STK17A (0.48) | STK17ASTK17BCHEK1FLT3ULK1 | |
| SCHEMBL3386164 | 0.80 | STK17A (0.60) | STK17ASTK17B | |
| SCHEMBL3388268 | 0.79 | SYK (0.52) | SYKSTK17ASTK17B | |
| SCHEMBL3387317 | 0.79 | SYK (0.52) | SYKSTK17ASTK17BULK1 | |
| Hydrochloric Acid SCHEMBL3386015 | 0.79 | STK17A (0.48) | STK17ASTK17BCHEK1FLT3ULK1 | |
| SCHEMBL3387331 | 0.78 | STK17A (0.52) | SYKSTK17ASTK17BULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056524-A1 | Compound | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056524-A1 | Compound | NR3C2, NR3C1, NR2E3 | PTK2B 456/4885SYK 627/4885PTK2 798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.