Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3434604 | 0.87 | ADRB2 (0.45) | ADRB2DRD2DRD1DRD4DRD3 | |
| SCHEMBL3392778 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3421814 | 0.77 | PTGS1 (0.35) | PTGS1PTGS2CNR2CNR1 | |
| SCHEMBL3757791 | 0.76 | MET (0.41) | SMN1; SMN2PTGS1PTGS2FFAR1FFAR4 | |
| SCHEMBL9972730 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2FFAR1FFAR4CNR2CNR1 | |
| SCHEMBL3757784 | 0.71 | SMN1; SMN2 (0.43) | SMN1; SMN2FFAR1FFAR4CNR2CNR1 | |
| SCHEMBL27801010 | 0.69 | BCHE (0.53) | SMN1; SMN2 | |
| SCHEMBL3754114 | 0.68 | KCNA3 (0.41) | SMN1; SMN2 | |
| SCHEMBL8408940 | 0.67 | SLC5A1 (0.41) | SMN1; SMN2PTGS1PTGS2 | |
| SCHEMBL2177920 | 0.67 | SMN1; SMN2 (0.33) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197832-A1 | NOVEL ARYL POTASSIUM CHANNEL BLOCKERS AND USES THEREOF | Bionomics Limited (AU) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009043117-A1 | NOVEL ARYL POTASSIUM CHANNEL BLOCKERS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2009-04-09 | — | — | WO | disclosed |