Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 3/20 | 0.42 |
| ▸ | NSD2 | O96028 | 3/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | S100A4 | P26447 | 5/20 | 0.38 |
| ▸ | CDC25B | P30305 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31201877 | 0.78 | TDP1 (0.52) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL404300 | 0.72 | PBRM1 (0.47) | TDP1GAACASP6ALDH1A1HSD17B10 | |
| SCHEMBL20657047 | 0.72 | SMN1; SMN2 (0.46) | MEN1KMT2ACASP6ALDH1A1HSD17B10 | |
| SCHEMBL407791 | 0.72 | NOTUM (0.43) | MEN1KMT2ACASP6ALDH1A1HTT | |
| SCHEMBL403090 | 0.72 | LDHA (0.47) | TDP1ALDH1A1HSD17B10CYP2A6 | |
| SCHEMBL28133533 | 0.72 | CYP1A2 (0.50) | TDP1GAACASP6ALDH1A1HSD17B10 | |
| SCHEMBL812826 | 0.71 | TDP2 (0.45) | MEN1THRBBLMKMT2ATDP1 | |
| SCHEMBL5553224 | 0.69 | — | — | |
| SCHEMBL29522058 | 0.69 | — | — | |
| SCHEMBL4451568 | 0.69 | NOTUM (0.46) | BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010514-B1 | 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2010-12-29 | — | — | EP | disclosed |