Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 11/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL403090 | 0.85 | LDHA (0.47) | NOTUMGRM5CYP2D6MAPK1 | |
| SCHEMBL6439475 | 0.82 | CNR2 (0.50) | NOTUMP2RX7CNR2GRM5CYP2D6 | |
| SCHEMBL17045019 | 0.75 | CNR2 (0.47) | NOTUMP2RX7CNR2GRM5CYP2D6 | |
| SCHEMBL20472405 | 0.72 | CNR2 (0.47) | NOTUMP2RX7CNR2GRM5CYP2D6 | |
| SCHEMBL4564446 | 0.71 | GRM5 (0.42) | P2RX7CNR2GRM5CYP2D6MAOA | |
| SCHEMBL17007732 | 0.70 | HTR2B (0.49) | P2RX7CNR2IDO1 | |
| SCHEMBL440943 | 0.70 | TSHR (0.52) | NOTUMP2RX7CNR2CYP2D6MAOA | |
| SCHEMBL404300 | 0.69 | PBRM1 (0.47) | MAPK1ADRA1AIDO1 | |
| SCHEMBL20657047 | 0.69 | SMN1; SMN2 (0.46) | MAPK1IDO1 | |
| SCHEMBL3386418 | 0.69 | MEN1 (0.47) | BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2117538-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-METHOXY-5- (5-TRIFLUOROMETHYL-TETRAZOL-I-YL-BENZYL) - (2S-PHENYL-PIPERIDIN-3S-YL-) | Glaxo Group Limited (GB) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008090114-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING 2-METHOXY-5- (5-TRIFLUOROMETHYL-TETRAZOL-I-YL-BENZYL) - (2S-PHENYL-PIPERIDIN-3S-YL-) | GLAXO GROUP LIMITED (GB) | 2008-07-31 | — | — | WO | disclosed |
| EP-1513535-B1 | CONTROLLED RELEASE FORMULATION OF LAMOTRIGINE | TORRENT PHARMACEUTICALS LTD (IN) | 2008-07-23 | — | — | EP | disclosed |
| WO-2005051350-A2 | WATER DISPERSIBLE TABLET | TORRENT PHARMACEUTICALS LIMITED (IN) | 2005-06-09 | — | — | WO | disclosed |
| EP-1513535-A2 | CONTROLLED RELEASE FORMULATION OF LAMOTRIGINE | Torrent Pharmaceuticals Ltd (IN) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003104192-A2 | CONTROLLED RELEASE FORMULATION OF LAMOTRIGINE | TORRENT PHARMACEUTICALS LIMITED (IN) | 2003-12-18 | — | — | WO | disclosed |