SCHEMBL3386871

SCHEMBL3386871

O=S(=O)(O)c1ccc(CCl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
CA2 P00918 8/20 0.50
CA1 P00915 6/20 0.50
TSHR P16473 2/20 0.50
ALDH1A1 P00352 2/20 0.50
NT5E P21589 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.48
TDP1 Q9NUW8 1/20 0.45
POLB P06746 1/20 0.42
CYP2D6 P10635 1/20 0.42
CA12 O43570 3/20 0.40
CA4 P22748 3/20 0.40
CA6 P23280 3/20 0.40
CA5A P35218 3/20 0.40
CA7 P43166 3/20 0.40
CA9 Q16790 3/20 0.40
CA14 Q9ULX7 3/20 0.40
CA5B Q9Y2D0 3/20 0.40
HSD17B10 Q99714 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL27785607 0.98 LMNA (0.50) LMNACA2CA1TSHRALDH1A1
SCHEMBL14830748 0.98 LMNA (0.50) LMNACA2CA1TSHRALDH1A1
Hydrochloric Acid SCHEMBL11584379 0.98 LMNA (0.50) LMNACA2CA1TSHRALDH1A1
SCHEMBL11335180 0.94 LMNA (0.46) LMNACA2CA1TSHRALDH1A1
SCHEMBL17212140 0.82 LMNA (0.48) LMNACA2CA1TSHRALDH1A1
SCHEMBL9619529 0.80 LMNA (0.56) LMNACA2CA1TSHRALDH1A1
SCHEMBL11583429 0.80 LMNA (0.56) LMNACA2CA1TSHRALDH1A1
SCHEMBL3539406 0.80 CYP3A4 (0.52) LMNACA2CA1TSHRALDH1A1
SCHEMBL150334 0.79 LMNA (0.77) LMNACA2CA1TSHRALDH1A1
SCHEMBL755114 0.79 CA2 (0.47) LMNACA2CA1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180539-A Pipelineization prepares the method and device of the chloro- 4- toluenesulfonic acid of 2- nitro -5- 浙江工业大学 2019-01-11 CN claimed
CN-108367529-A Light flame-retardant thermoplastic structure 施内勒公司 2018-08-03 CN claimed
CN-105541667-B The method that continuous conduit metaplasia produces CLT acid itrated compound 浙江秦燕科技股份有限公司 2018-04-20 CN claimed
JP-60045246-A None JP disclosed
CN-119060221-A Sulfonic acid functionalized polymer, ion exchange membrane and application thereof 佛山绿动氢能科技有限公司 2024-12-03 CN disclosed
CN-113797842-B Hydrocarbyl aryl anionic nonionic surfactant and preparation method thereof 中国石油化工股份有限公司 2023-08-29 CN disclosed
US-20220220151-A1 METHOD FOR PREPARING PEPTIDES SULFOTOOLS GMBH (DE) 2022-07-14 US disclosed
US-11319340-B2 Method for preparing peptides SULFOTOOLS GMBH (DE) 2022-05-03 US disclosed
CN-109689051-B Use of inhibitors of mitochondrial activity for the treatment of acute myeloid leukemia with poor prognosis 蒙特利尔大学 2022-03-29 CN disclosed
CN-111234818-B Method for synthesizing surface functional group modified carbon quantum dots and application of carbon quantum dots in nano oil displacement 西南石油大学 2022-03-18 CN disclosed
CN-113797842-A Alkyl aryl anionic nonionic surfactant and preparation method thereof 中国石油化工股份有限公司 2021-12-17 CN disclosed
US-5075488-A Fungicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-12-24 US disclosed
EP-0128006-B1 A SOIL-DISEASE-CONTROLLING AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-09-18 EP disclosed
US-4709052-A FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-11-24 US disclosed
JP-S6045246-A FORMATION OF RESIST PATTERN OKI ELECTRIC IND CO LTD 1985-03-11 JP disclosed
EP-0128006-A2 A soil-disease-controlling agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-12-12 EP disclosed
US-4418015-A Phthalocyanine reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1983-11-29 US disclosed
EP-0053320-A2 Process for the preparation of phthalocyanin compounds BAYER AG (DE) 1982-06-09 EP disclosed
EP-0047863-A2 Reactive phthalocyanine hyes, process for their preparation and their use in dyeing materials containing hydroxyle groups and/or nitrogen BAYER AG (DE) 1982-03-24 EP disclosed
JP-S0645246-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319340-B2 Method for preparing peptides VIP, DNPEP, PEPD LMNA 2611/4885CA2 466/4885CA1 156/4885
US-20220220151-A1 METHOD FOR PREPARING PEPTIDES VIP, DNPEP, PEPD LMNA 1913/4885CA2 1059/4885CA1 223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.