Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 2/20 | 0.32 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331681 | 0.98 | LIPG (0.40) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| Water SCHEMBL187670 | 0.97 | LIPG (0.39) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| Iodide SCHEMBL21808913 | 0.97 | LIPG (0.39) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL766982 | 0.97 | LIPG (0.39) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| Bicarbonate SCHEMBL28525416 | 0.91 | CYSLTR2 (0.41) | LIPGCYSLTR2CYSLTR1 | |
| Bromide SCHEMBL20163234 | 0.90 | LIPG (0.47) | LIPGTLR8CYSLTR2CYSLTR1NR1H2 | |
| Bromide SCHEMBL11614736 | 0.90 | LIPG (0.47) | LIPGTLR8CYSLTR2CYSLTR1NR1H2 | |
| Bromide SCHEMBL20163268 | 0.90 | LIPG (0.47) | LIPGTLR8CYSLTR2CYSLTR1NR1H2 | |
| SCHEMBL28501218 | 0.90 | LIPG (0.46) | LIPGTLR8CYSLTR2CYSLTR1NR1H2 | |
| Acetic Acid SCHEMBL28915072 | 0.89 | CYSLTR2 (0.40) | LIPGCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528850-A | Preparation and application methods of novel insulating material cross-linking agent | 哈尔滨理工大学 | 2025-02-28 | — | — | CN | claimed |
| CN-115029103-B | Preparation method and application of mildew-proof water-resistant soybean protein adhesive | 北京林业大学 | 2023-05-26 | — | — | CN | claimed |
| CN-115029103-A | Preparation method and application of mildew-proof water-resistant soybean protein adhesive | 北京林业大学 | 2022-09-09 | — | — | CN | claimed |
| CN-114249896-A | Allyl-terminated aryl sulfone ether polymer and preparation method thereof | 兰溪聪普新材料有限公司 | 2022-03-29 | — | — | CN | claimed |
| US-20240002612-A1 | FIBER-REINFORCED PULTRUSION-MOLDED ARTICLE | TORAY INDUSTRIES, INC. (JP) | 2024-01-04 | — | — | US | disclosed |
| EP-4257624-A1 | FIBER-REINFORCED PULTRUSION-MOLDED ARTICLE | Toray Industries, Inc. (JP) | 2023-10-11 | — | — | EP | disclosed |
| CN-116507653-A | Drawn fiber-reinforced molded article | 东丽株式会社 | 2023-07-28 | — | — | CN | disclosed |
| CN-115029103-B | Preparation method and application of mildew-proof water-resistant soybean protein adhesive | 北京林业大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-115029103-B | Preparation method and application of mildew-proof water-resistant soybean protein adhesive | 北京林业大学 | 2023-05-26 | — | — | CN | disclosed |
| EP-4166712-A1 | METHOD FOR PRODUCING COAGULATED MATERIAL | DIC Corporation (JP) | 2023-04-19 | — | — | EP | disclosed |
| CN-115029103-A | Preparation method and application of mildew-proof water-resistant soybean protein adhesive | 北京林业大学 | 2022-09-09 | — | — | CN | disclosed |
| CN-115029103-A | Preparation method and application of mildew-proof water-resistant soybean protein adhesive | 北京林业大学 | 2022-09-09 | — | — | CN | disclosed |
| EP-0535231-A1 | PYRIMIDINE NUCLEOSIDE DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5194608-A | Hypotensive agents; inhibits renin-angiotensin system | SHIONOGI & CO., LTD. (JP) | 1993-03-16 | — | — | US | disclosed |
| EP-0468641-A2 | Renin inhibiting dipeptide derivatives, their preparation and pharmaceutical preparations containing them | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-4973726-A | CHEMICAL INTERMEDIATES, IMINOMALONIC ACID ESTER | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-27 | — | — | US | disclosed |
| US-4909830-A | With aromatic substitution in position 5 | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-20 | — | — | US | disclosed |
| US-4328170-A | Process for preparing an α-cyanoacrylate | MATSUMOTO SEIYAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-05-04 | — | — | US | disclosed |
| US-4272533-A | ANTIDIABETIC, ANTIOBESITY | SANDOZ LTD. (CH) | 1981-06-09 | — | — | US | disclosed |
| US-4088763-A | VASCULAR AND CARDIAC DISEASES | KNOLL A.G. CHEMISCHE FABRIKEN (DT) | 1978-05-09 | — | — | US | disclosed |