Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 2/20 | 0.32 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL331681 | 0.98 | LIPG (0.40) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL766982 | 0.97 | LIPG (0.39) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| Bromide SCHEMBL3386923 | 0.97 | LIPG (0.39) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| Iodide SCHEMBL21808913 | 0.97 | LIPG (0.39) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| Cyanate SCHEMBL10998064 | 0.92 | LIPG (0.37) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| Sulfuric Acid SCHEMBL17272950 | 0.91 | LIPG (0.36) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| Bicarbonate SCHEMBL28525416 | 0.91 | CYSLTR2 (0.41) | LIPGCYSLTR2CYSLTR1 | |
| SCHEMBL28501218 | 0.90 | LIPG (0.46) | LIPGTLR8CYSLTR2CYSLTR1NR1H2 | |
| Acetic Acid SCHEMBL28915072 | 0.89 | CYSLTR2 (0.40) | LIPGCYSLTR2CYSLTR1 | |
| Sulfuric Acid SCHEMBL17272962 | 0.89 | LIPG (0.37) | LIPGTLR8CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058450-A | C (sp) in benzene ring2) Method for deuteration of the H bond | 云南大学 | 2025-05-30 | — | — | CN | claimed |
| CN-119219550-A | Reduction method of carboxylic ester compound | 云南大学 | 2024-12-31 | — | — | CN | claimed |
| CN-113501779-B | Method for selectively removing benzyl, allyl and propargyl protecting groups by visible light or near visible light | 云南大学 | 2023-06-23 | — | — | CN | claimed |
| CN-111825103-B | Fluorine-containing high-silicon Y molecular sieve and preparation method thereof | 中国科学院大连化学物理研究所 | 2022-04-12 | — | — | CN | claimed |
| CN-111825102-B | Dry glue conversion synthesis method of high-silicon Y molecular sieve | 中国科学院大连化学物理研究所 | 2022-03-22 | — | — | CN | claimed |
| CN-113501779-A | Method for selectively removing benzyl, allyl and propargyl protecting groups initiated by visible light or near visible light | 云南大学 | 2021-10-15 | — | — | CN | claimed |
| CN-111825102-A | Dry glue conversion synthesis method of high-silicon Y molecular sieve | 中国科学院大连化学物理研究所 | 2020-10-27 | — | — | CN | claimed |
| CN-111825103-A | Fluorine-containing high-silicon Y molecular sieve and preparation method thereof | 中国科学院大连化学物理研究所 | 2020-10-27 | — | — | CN | claimed |
| CN-111039910-A | Photoinitiated method for synthesizing 3-aryl flavone or coumarin compound and application thereof | 云南大学 | 2020-04-21 | — | — | CN | claimed |
| CN-122037155-A | Hollow container and method for producing polycarbonate resin | 三菱化学株式会社 | 2026-05-15 | — | — | CN | disclosed |
| EP-2371877-B1 | POLYCARBONATE RESIN, POLYCARBONATE RESIN COMPOSITION, OPTICAL FILM, AND POLYCARBONATE RESIN MOLDED ARTICLE | MITSUBISHI CHEM CORP (JP) | 2026-04-29 | — | — | EP | disclosed |
| US-20260098129-A1 | THERMOPLASTIC RESIN AND MOLDED BODY CONTAINING THERMOPLASTIC RESIN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2026-04-09 | — | — | US | disclosed |
| US-20260071030-A1 | THERMOPLASTIC RESIN, MOLDED BODY CONTAINING THERMOPLASTIC RESIN, AND OPTICAL LENS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2026-03-12 | — | — | US | disclosed |
| US-20260062520-A1 | THERMOPLASTIC RESIN AND MOLDED OBJECT INCLUDING THERMOPLASTIC RESIN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2026-03-05 | — | — | US | disclosed |
| EP-0738579-A2 | Production method of polycarbonate | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1996-10-23 | — | — | EP | disclosed |
| EP-0716347-A1 | Developer for photosensitive lithographic printing plate | FUJI PHOTO FILM CO., LTD. (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5403801-A | Contacting zeolite with either aqueous solution of ammonium salts and base, or ammonia water | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-04-04 | — | — | US | disclosed |
| US-5212302-A | Catalytic reaction of cyclohexanone oxime | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| EP-0494535-A1 | Process for producing epsilon-caprolactam and activating solid catalysts therefor | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-07-15 | — | — | EP | disclosed |
| EP-0171787-A1 | Process for production of aziridine-2-carboxylic acid amide | RESEARCH ASSOCIATION FOR UTILIZATION OF LIGHT OIL (JP) | 1986-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062520-A1 | THERMOPLASTIC RESIN AND MOLDED OBJECT INCLUDING THERMOPLASTIC RESIN | RER1, PUF60, SEM1 | SLC6A2 4422/4885SLC6A4 4765/4885LIPG 4855/4885 |
| US-20260071030-A1 | THERMOPLASTIC RESIN, MOLDED BODY CONTAINING THERMOPLASTIC RESIN, AND OPTICAL LENS | DERL1, WDR1, RIF1 | SLC6A2 4428/4885SLC6A4 4610/4885LIPG 3970/4885 |
| US-20260098129-A1 | THERMOPLASTIC RESIN AND MOLDED BODY CONTAINING THERMOPLASTIC RESIN | RER1, EIF2AK1, RIOK1 | SLC6A2 4124/4885SLC6A4 4618/4885LIPG 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.