SCHEMBL3387159

SCHEMBL3387159

CNC(SC(C)C)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
RNPEP Q9H4A4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5729590 0.74
SCHEMBL3394612 0.68
Hydrochloric Acid SCHEMBL2971887 0.67
Hydrochloric Acid SCHEMBL1027048 0.67
Hydrochloric Acid SCHEMBL3465819 0.67
Hydrochloric Acid SCHEMBL32662667 0.67
SCHEMBL10524533 0.67 TP53 (0.42) TP53RNPEP
SCHEMBL11940981 0.67 TP53 (0.42) TP53RNPEP
SCHEMBL12285652 0.67
SCHEMBL589943 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1560558-B1 USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH LG HOUSEHOLD & HEALTH CARE LTD (KR) 2010-12-29 EP claimed
EP-1560558-A4 USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH LG HOUSEHOLD & HEALTH CARE LTD (KR) 2008-09-24 EP claimed
JP-2006508103-A 2006-03-09 JP claimed
US-6987090-B2 Use of 3-position cyclosporin derivatives for hair growth LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2006-01-17 US claimed
EP-1560558-A1 USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH LG Household & Health Care Ltd. (KR) 2005-08-10 EP claimed
WO-2004041221-A1 USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2004-05-21 WO claimed
US-20040087496-A1 Use of 3-position cyclosporin derivatives for hair growth LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2004-05-06 US claimed
US-20180155360-A1 ETHER ANALOGUES OF GALIELLALACTONE GLACTONE PHARMA DEVELOPMENT AB (SE) 2018-06-07 US disclosed
EP-1560558-B1 USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH LG HOUSEHOLD & HEALTH CARE LTD (KR) 2010-12-29 EP disclosed
EP-1560558-A4 USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH LG HOUSEHOLD & HEALTH CARE LTD (KR) 2008-09-24 EP disclosed
US-6987090-B2 Use of 3-position cyclosporin derivatives for hair growth LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2006-01-17 US disclosed
EP-1560558-A1 USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH LG Household & Health Care Ltd. (KR) 2005-08-10 EP disclosed
WO-2004041221-A1 USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2004-05-21 WO disclosed
US-20040087496-A1 Use of 3-position cyclosporin derivatives for hair growth LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2004-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040087496-A1 Use of 3-position cyclosporin derivatives for hair growth TPMT, BHMT2, SUCLG1 TP53 2752/4885RNPEP 1093/4885
US-20180155360-A1 ETHER ANALOGUES OF GALIELLALACTONE GALE, GALK1, PGLS TP53 1680/4885RNPEP 3405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.