SCHEMBL3387298

SCHEMBL3387298

O=C(O)CC[C@@H](NCc1ccccc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ NAALAD2 Q9Y3Q0 5/20 0.60
▸ FOLH1 Q04609 5/20 0.58
▸ MEP1B Q16820 2/20 0.58
▸ CPA3 P15088 1/20 0.53
▸ GGH Q92820 1/20 0.53
▸ GAA P10253 2/20 0.51
▸ MMP9 P14780 1/20 0.50
▸ MMP8 P22894 1/20 0.50
▸ MMP13 P45452 1/20 0.50
▸ ADAMTS4 O75173 1/20 0.50
▸ MAPT P10636 1/20 0.48
▸ RIMKLA Q8IXN7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL869873 1.00 NAALAD2 (0.60) NAALAD2FOLH1MEP1BCPA3GGH
SCHEMBL1818651 1.00 NAALAD2 (0.60) NAALAD2FOLH1MEP1BCPA3GGH
SCHEMBL30213700 0.91 NAALAD2 (0.51) NAALAD2FOLH1MEP1BCPA3GGH
SCHEMBL31419850 0.88 MEP1B (0.61) NAALAD2FOLH1MEP1BCPA3GGH
SCHEMBL461572 0.87 KMT2A (0.54) NAALAD2FOLH1MEP1BMMP9MMP8
SCHEMBL461571 0.87 KMT2A (0.54) NAALAD2FOLH1MEP1BMMP9MMP8
SCHEMBL2251929 0.87 MEP1B (0.52) NAALAD2FOLH1MEP1BCPA3GGH
SCHEMBL6566486 0.85 FOLH1 (0.61) NAALAD2FOLH1MEP1BGAAMMP9
SCHEMBL5577137 0.85 MEP1B (0.48) NAALAD2FOLH1MEP1BGGHRIMKLA
SCHEMBL5577139 0.85 MEP1B (0.48) NAALAD2FOLH1MEP1BGGHRIMKLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150232616-A1 HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS INTEZYNE TECHNOLOGIES, INC. 2015-08-20 — — US claimed
US-8980326-B2 Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents INTEZYNE TECHNOLOGIES, INC. (US) 2015-03-17 — — US claimed
EP-2359862-B1 Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents INTEZYNE TECHNOLOGIES INC (US) 2013-07-24 — — EP claimed
US-20100324259-A1 HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS INTEZYNE TECHNOLOGIES, INC. (US) 2010-12-23 — — US claimed
EP-2073850-B1 HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS INTEZYNE TECHNOLOGIES INC (US) 2010-10-27 — — EP claimed
US-12254963-B2 Method for determination of the anisotropic parameters for the configuration of organic molecules embedded in alignment media MAX-PLACK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2025-03-18 — — US disclosed
WO-2023227633-A1 AMPHIPHILIC POLY(AMINO ACID) LINEAR BLOCK COPOLYMERS AND NANOPARTICLES THEREOF FOR DRUG DELIVERY APPLICATIONS NANOTHERA BIOSCIENCES, INC. (US) 2023-11-30 — — WO disclosed
CN-109844971-B Structure for piezoelectric element, string-like piezoelectric element, cloth-like piezoelectric element, and device using same 帝人株式会社 2023-07-28 — — CN disclosed
US-20230067122-A1 Method for Determination of the Anisotropic Parameters for the Configuration of Organic Molecules Embedded in Alignment Media MAX-PLACK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2023-03-02 — — US disclosed
EP-4090956-A1 METHOD FOR DETERMINATION OF THE ANISOTROPIC PARAMETERS FOR THE CONFIGURATION OF ORGANIC MOLECULES EMBEDDED IN ALIGNMENT MEDIA Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2022-11-23 — — EP disclosed
US-11339130-B1 Calpain modulators and therapeutic uses thereof BLADE THERAPEUTICS, INC. (US) 2022-05-24 — — US disclosed
US-10934261-B2 Calpain modulators and therapeutic uses thereof BLADE THERAPEUTICS, INC. (US) 2021-03-02 — — US disclosed
WO-2013154774-A1 BLOCK COPOLYMERS FOR STABLE MICELLES INTEZYNE TECHNOLOGIES, INC. (US) 2013-10-17 — — WO disclosed
EP-1392755-A1 LIPID-POLYMER-CONJUGATES COMPOSITIONS YAMANOUCHI EUROPE B.V. (NL) 2004-03-03 — — EP disclosed
EP-1392756-A2 LIPID-POLYMER-CONJUGATES Yamanouchi Europe B.V. (NL) 2004-03-03 — — EP disclosed
WO-2002098952-A1 LIPID-POLYMER-CONJUGATES COMPOSITIONS YAMANOUCHI EUROPE B.V. (NL) 2002-12-12 — — WO disclosed
WO-2002098951-A2 LIPID-POLYMER-CONJUGATES YAMANOUCHI EUROPE B.V. (NL) 2002-12-12 — — WO disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 — — EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 — — WO disclosed
US-4127540-A Novel derivatives of δ-endorphins, intermediates therefor, and compositions and methods employing said derivatives VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10934261-B2 Calpain modulators and therapeutic uses thereof CAPNS1, CAPN9, CAPN1 NAALAD2 604/4885FOLH1 1680/4885MEP1B 1421/4885
US-11339130-B1 Calpain modulators and therapeutic uses thereof CAPNS1, CAPN9, CAPN1 NAALAD2 604/4885FOLH1 1680/4885MEP1B 1421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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