Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 2/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.46 |
| ▸ | ITGAV | P06756 | 3/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.45 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | GGH | Q92820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577139 | 1.00 | MEP1B (0.48) | MEP1BITGB1ITGA5NAALAD2ITGB3 | |
| SCHEMBL10421273 | 0.87 | NAALAD2 (0.45) | MEP1BNAALAD2FOLH1RIMKLADHFR | |
| SCHEMBL869873 | 0.85 | NAALAD2 (0.60) | MEP1BNAALAD2FOLH1RIMKLAGGH | |
| SCHEMBL1818651 | 0.85 | NAALAD2 (0.60) | MEP1BNAALAD2FOLH1RIMKLAGGH | |
| SCHEMBL3387298 | 0.85 | NAALAD2 (0.60) | MEP1BNAALAD2FOLH1RIMKLAGGH | |
| SCHEMBL8612645 | 0.84 | FFAR1 (0.50) | MEP1BNAALAD2FOLH1RIMKLA | |
| SCHEMBL6566486 | 0.84 | FOLH1 (0.61) | MEP1BNAALAD2FOLH1 | |
| SCHEMBL11586552 | 0.84 | ITGB1 (0.50) | MEP1BITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL1097115 | 0.82 | ITGB1 (0.51) | MEP1BITGB1ITGA5ITGB3ITGAV | |
| SCHEMBL29788283 | 0.81 | ALDH1A1 (0.50) | MEP1BNAALAD2FOLH1RIMKLAGGH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101973995-A | Method for recycling waste water in production of folic acid | SHANGHAI ECUST BIOMEDICINE CO LTD | 2011-02-16 | — | — | CN | disclosed |
| US-20070141635-A1 | Novel translocation assay | GARVAN INSTITUTE OF MEDICAL RESEARCH (AU) | 2007-06-21 | — | — | US | disclosed |
| EP-0416232-B1 | Stable injectable pharmaceutical formulation for folic acid and leucovorin salts and method | AMERICAN CYANAMID CO (US) | 1995-08-16 | — | — | EP | disclosed |
| US-5173488-A | Tromethamine and monothioglycerol as buffers and antioxidants | AMERICAN CYANAMID COMPANY (US) | 1992-12-22 | — | — | US | disclosed |
| EP-0416232-A2 | Stable injectable pharmaceutical formulation for folic acid and leucovorin salts and method | AMERICAN CYANAMID COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |