Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.56 |
| ▸ | GABRD | O14764 | 2/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.56 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.56 |
| ▸ | GABRE | P78334 | 2/20 | 0.56 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.56 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.56 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.56 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.56 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8634071 | 0.92 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL60727 | 0.85 | — | — | |
| SCHEMBL6687775 | 0.85 | — | — | |
| SCHEMBL9420958 | 0.85 | ALDH1A1 (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14498560 | 0.85 | — | — | |
| Bicarbonate SCHEMBL7084977 | 0.84 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL1839190 | 0.82 | — | — | |
| SCHEMBL29415522 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL28145906 | 0.82 | — | — | |
| SCHEMBL11627934 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456267-A1 | AQUEOUS POLYURETHANE DISPERSIONS OBTAINED BY THE USE OF CAESIUM SALTS | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-15 | — | — | EP | claimed |
| WO-2004003045-A1 | AQUEOUS POLYURETHANE DISPERSIONS | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-08 | — | — | WO | claimed |
| WO-2003050156-A1 | AQUEOUS POLYURETHANE DISPERSIONS OBTAINED BY THE USE OF CAESIUM SALTS | BASF AKTIENGESELLSCHAFT (DE) | 2003-06-19 | — | — | WO | claimed |
| EP-3390481-B1 | AQUEOUS POLYMER DISPERSION FOR ADHESIVE COMPOUNDS | BASF SE (DE) | 2020-05-13 | — | — | EP | disclosed |
| EP-3390481-A1 | AQUEOUS POLYMER DISPERSION FOR ADHESIVE COMPOUNDS | BASF SE (DE) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017102777-A1 | AQUEOUS POLYMER DISPERSION FOR ADHESIVE COMPOUNDS | BASF SE (DE) | 2017-06-22 | — | — | WO | disclosed |
| EP-1373350-B1 | USE OF ANIONIC POLYMERS THAT CARRY URETHANE AND/OR UREA GROUPS FOR MODIFYING SURFACES | BASF SE (DE) | 2010-12-15 | — | — | EP | disclosed |
| EP-1427863-A1 | LEATHER SEASONING AGENT | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-16 | — | — | EP | disclosed |
| EP-1373350-A1 | USE OF ANIONIC POLYMERS THAT CARRY URETHANE AND/OR UREA GROUPS FOR MODIFYING SURFACES | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2003023071-A1 | LEATHER SEASONING AGENT | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-20 | — | — | WO | disclosed |
| WO-2002070578-A1 | USE OF ANIONIC POLYMERS THAT CARRY URETHANE AND/OR UREA GROUPS FOR MODIFYING SURFACES | BASF AKTIENGESELLSCHFT (DE) | 2002-09-12 | — | — | WO | disclosed |