Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.54 |
| ▸ | GABRD | O14764 | 2/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.54 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.54 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.54 |
| ▸ | GABRE | P78334 | 2/20 | 0.54 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.54 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.54 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.54 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.54 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL3387529 | 0.92 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14498560 | 0.83 | — | — | |
| SCHEMBL6687775 | 0.83 | — | — | |
| SCHEMBL9420958 | 0.83 | ALDH1A1 (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL60727 | 0.83 | — | — | |
| SCHEMBL18279795 | 0.81 | TDP1 (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Acetic Acid SCHEMBL28331954 | 0.81 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Acetic Acid SCHEMBL21227 | 0.80 | ALDH1A1 (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Acetic Acid SCHEMBL12474237 | 0.80 | ALDH1A1 (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Acetic Acid SCHEMBL8817349 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540990-B1 | Tablet-shaped processing agent and method for processing silver halide photographic light sensitive materials | KONISHIROKU PHOTO IND (JP) | 1998-07-15 | — | — | EP | disclosed |
| US-5366853-A | Bleaches for photographic films | KONICA CORPORATION (JP) | 1994-11-22 | — | — | US | disclosed |
| US-5362610-A | Photographic processing agent | KONICA CORPORATION (JP) | 1994-11-08 | — | — | US | disclosed |
| EP-0540990-A1 | Tablet-shaped processing agent and method for processing silver halide photographic light sensitive materials | KONICA CORPORATION (JP) | 1993-05-12 | — | — | EP | disclosed |
| EP-0540296-A1 | Photographic processing agent | KONICA CORPORATION (JP) | 1993-05-05 | — | — | EP | disclosed |