Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | BCL6 | P41182 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261594 | 0.79 | SIGMAR1 (0.46) | POLBKDM4EALDH1A1 | |
| SCHEMBL3387671 | 0.74 | POLB (0.69) | POLBKMT2AHPGDMEN1KDM4E | |
| SCHEMBL29619559 | 0.72 | ALDH1A1 (0.39) | KMT2AHPGDMEN1KDM4EALDH1A1 | |
| SCHEMBL9510331 | 0.71 | POLB (0.61) | POLBKMT2AHPGDMEN1KDM4E | |
| SCHEMBL12770967 | 0.70 | POLB (0.64) | POLBKMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL13221831 | 0.69 | POLB (0.58) | POLBKMT2AHPGDMEN1KDM4E | |
| SCHEMBL13902268 | 0.69 | POLB (0.50) | POLBALDH1A1GAALMNAMAPT | |
| SCHEMBL18557515 | 0.68 | POLB (0.57) | POLBKMT2AHPGDMEN1KDM4E | |
| SCHEMBL16049989 | 0.68 | MAPK1 (0.54) | POLBKMT2AHPGDMEN1KDM4E | |
| SCHEMBL18649398 | 0.68 | POLB (0.60) | POLBKMT2AHPGDMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |