Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306135 | 0.81 | GNAI3 (0.31) | GNAI3GNAO1GNAI1 | |
| SCHEMBL6627321 | 0.78 | POLB (0.32) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL8205709 | 0.78 | SIGMAR1 (0.32) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL8370582 | 0.77 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL467885 | 0.77 | ADRB1 (0.31) | — | |
| SCHEMBL9363442 | 0.77 | ADRB1 (0.31) | — | |
| SCHEMBL8078414 | 0.77 | ADRB1 (0.31) | — | |
| SCHEMBL1264415 | 0.76 | — | — | |
| SCHEMBL14736906 | 0.76 | — | — | |
| SCHEMBL13265256 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202876-B2 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2012-06-19 | — | — | US | claimed |
| CN-101175785-B | Hydrocarbon or hydrofluorocarbon blown ASTM E-84 class I rigid polyurethane foams | BAYER MATERIALSCIENCE LLC | 2011-02-09 | — | — | CN | claimed |
| US-20100029605-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2010-02-04 | — | — | US | claimed |
| CN-101522661-A | Compounds and compositions as protein kinase inhibitors | IRM LLC (VG) | 2009-09-02 | — | — | CN | claimed |
| EP-2057146-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2009-05-13 | — | — | EP | claimed |
| CN-101316875-A | Water-blown, flame retardant rigid polyurethane foam | BAYER MATERIALSCIENCE LLC (US) | 2008-12-03 | — | — | CN | claimed |
| CN-101175785-A | Hydrocarbon or hydrofluorocarbon blown ASTM E-84 class i rigid polyurethane foams | BAYER MATERIALSCIENCE LLC (US) | 2008-05-07 | — | — | CN | claimed |
| WO-2008042639-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2008-04-10 | — | — | WO | claimed |
| CN-1179994-C | Low density water sparkling polyurethane sparkling material for energy absorption | — | 2004-12-15 | — | — | CN | claimed |
| CN-1333302-A | Low density water sparkling polyurethane sparkling material for energy absorption | BAYER AG (US) | 2002-01-30 | — | — | CN | claimed |
| CN-103131185-B | A kind of cured liquid sealant composition and its preparation method and application on demand | 密封剂欧洲有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-101687775-B | Aldimines and compositions comprising aldamine | SIKA TECHNOLOGY AG | 2015-05-06 | — | — | CN | disclosed |
| CN-104066763-A | Low density polyurethane shoe sole or sole portion with high resilience and low compression set | BASF SE | 2014-09-24 | — | — | CN | disclosed |
| CN-101765583-B | Aldimines comprising hydroxyl groups, and compositions containing aldimine | SIKA TECHNOLOGY AG | 2014-06-04 | — | — | CN | disclosed |
| CN-101883753-B | Aromatic aldimines and polyurethane compositions which contain aldimine | SIKA TECHNOLOGY AG | 2014-06-04 | — | — | CN | disclosed |
| EP-1375629-A2 | A method of improving the compatibility of a fuel additive composition containing a Mannich condensation product | Chevron Oronite Company LLC (US) | 2004-01-02 | — | — | EP | disclosed |
| US-20040000089-A1 | Method of improving the compatibility of a fuel additive composition containing a mannich condensation product | CHEVRON ORONITE COMPANY LLC | 2004-01-01 | — | — | US | disclosed |
| US-20030172582-A1 | Fuel additive compositions containing a mannich condensation product, a poly (oxyalkylene) monool, and a carboxylic acid | CHEVRON ORONITE COMPANY LLC | 2003-09-18 | — | — | US | disclosed |
| EP-1323814-A2 | Fuel additive compositions containing a Mannich condensation product, a poly(oxyalkylene) monool, and a carboxylic acid | Chevron Oronite Company LLC (US) | 2003-07-02 | — | — | EP | disclosed |
| CN-1333302-A | Low density water sparkling polyurethane sparkling material for energy absorption | BAYER AG (US) | 2002-01-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029605-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | FYN, ABL2, LCK | SIGMAR1 4527/4885GNAI3 1142/4885GNAO1 2765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.