Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480828 | 0.82 | ALPL (0.44) | NPC1RAB9ATP53HPGDNPSR1 | |
| SCHEMBL9415766 | 0.82 | ALPL (0.44) | NPC1RAB9ATP53HPGDNPSR1 | |
| SCHEMBL29111148 | 0.77 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL28408503 | 0.77 | MAPT (0.33) | RAB9ATP53HPGDL3MBTL1MEN1 | |
| SCHEMBL5968449 | 0.77 | AR (0.30) | POLBCYP2C9 | |
| SCHEMBL28789387 | 0.76 | HPGD (0.48) | NPC1RAB9ATP53HPGDMAPK1 | |
| SCHEMBL8897608 | 0.76 | KMT2A (0.47) | NPC1RAB9ATP53HPGDNPSR1 | |
| SCHEMBL17495613 | 0.74 | CSNK2A1 (0.45) | MEN1ALDH1A1KMT2ASMN1; SMN2ALPL | |
| SCHEMBL1312553 | 0.74 | LDHA (0.52) | NPC1RAB9ATP53HPGDTDP1 | |
| SCHEMBL15593982 | 0.73 | IDO1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722592-B2 | Use of triazoles in reducing cobalt leaching from cobalt-containing metal working tools | Wincom, Inc. (US) | 2014-05-13 | — | — | US | disclosed |
| US-20100022424-A1 | USE OF TRIAZOLES IN REDUCING COBALT LEACHING FROM COBALT-CONTAINING METAL WORKING TOOLS | Wincom, Inc. (US) | 2010-01-28 | — | — | US | disclosed |