SCHEMBL3388998

SCHEMBL3388998

CCOC(=O)C1CCCN1C(=O)C(C)N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 2/20 0.51
DPP4 P27487 3/20 0.50
FAP Q12884 2/20 0.50
DPP7 Q9UHL4 2/20 0.50
PREP P48147 1/20 0.50
DPP8 Q6V1X1 1/20 0.50
DPP9 Q86TI2 1/20 0.50
PEPD P12955 3/20 0.46
ALDH1A1 P00352 1/20 0.46
ACE P12821 8/20 0.44
REN P00797 3/20 0.44
LMNA P02545 2/20 0.44
KDM4E B2RXH2 1/20 0.44
F2 P00734 1/20 0.44
LTA4H P09960 1/20 0.44
MAPT P10636 1/20 0.44
ALOX15 P16050 1/20 0.44
PTGS1 P23219 1/20 0.44
HTR2A P28223 1/20 0.44
PTGS2 P35354 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3388993 0.99 FKBP1A (0.50) FKBP1ADPP4FAPDPP7PREP
Hydrochloric Acid SCHEMBL7361206 0.99 FKBP1A (0.50) FKBP1ADPP4FAPDPP7PREP
SCHEMBL17208363 0.88 FKBP1A (0.53) FKBP1APEPDALDH1A1ACEREN
SCHEMBL18630164 0.87 RAB9A (0.56) DPP4FAPDPP7PREPDPP8
SCHEMBL4681406 0.87 FKBP1A (0.52) FKBP1APEPDALDH1A1ACEREN
SCHEMBL4681408 0.87 FKBP1A (0.52) FKBP1APEPDALDH1A1ACEREN
SCHEMBL14067710 0.86 DPP4 (0.59) FKBP1ADPP4FAPDPP7DPP8
SCHEMBL17345170 0.86 FKBP1A (0.46) FKBP1ADPP4FAPDPP7PREP
SCHEMBL683425 0.85 FKBP1A (0.51) FKBP1APEPDALDH1A1ACEREN
SCHEMBL13981344 0.84 FKBP1A (0.59) FKBP1AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1737819-B1 AMINO ACID AND PEPTIDE CONJUGATES OF ARYLALKYLIC ACIDS FOR COSMETIC USE DSM IP ASSETS BV (NL) 2010-12-22 EP disclosed
US-20100099727-A1 Amino acid and peptide conjugates of arylalkylic acids for cosmetic use DSM IP ASSETS B.V. (NL) 2010-04-22 US disclosed
US-20080234344-A1 Amino Acid and Peptide Conjugates of Arylalkylic Acids for Cosmetic Use DSM IP ASSETS B.V. (NL) 2008-09-25 US disclosed
EP-1737819-A1 AMINO ACID AND PEPTIDE CONJUGATES OF ARYLALKYLIC ACIDS FOR COSMETIC USE DSMIP Assets B.V. (NL) 2007-01-03 EP disclosed
WO-2005092850-A1 AMINO ACID AND PEPTIDE CONJUGATES OF ARYLALKYLIC ACIDS FOR COSMETIC USE DSM IP ASSETS B.V. (NL) 2005-10-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080234344-A1 Amino Acid and Peptide Conjugates of Arylalkylic Acids for Cosmetic Use NGLY1, HRH4, C3AR1 FKBP1A 2083/4885DPP4 1193/4885FAP 824/4885
US-20100099727-A1 Amino acid and peptide conjugates of arylalkylic acids for cosmetic use NGLY1, HRH4, C3AR1 FKBP1A 2083/4885DPP4 1193/4885FAP 824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.