SCHEMBL683425

SCHEMBL683425

CCOC(=O)[C@@H]1CCCN1C(=O)C(C)S

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 2/20 0.51
ACE P12821 8/20 0.48
REN P00797 3/20 0.48
LMNA P02545 2/20 0.48
KDM4E B2RXH2 1/20 0.48
F2 P00734 1/20 0.48
LTA4H P09960 1/20 0.48
MAPT P10636 1/20 0.48
PEPD P12955 1/20 0.48
ALOX15 P16050 1/20 0.48
PTGS1 P23219 1/20 0.48
HTR2A P28223 1/20 0.48
PTGS2 P35354 1/20 0.48
HRH1 P35367 1/20 0.48
THPO P40225 1/20 0.48
PMP22 Q01453 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ACE2 Q9BYF1 1/20 0.48
ALDH1A1 P00352 1/20 0.46
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17208363 0.88 FKBP1A (0.53) FKBP1AACERENLMNAKDM4E
SCHEMBL4681406 0.87 FKBP1A (0.52) FKBP1AACERENLMNAKDM4E
SCHEMBL4681408 0.87 FKBP1A (0.52) FKBP1AACERENLMNAKDM4E
SCHEMBL683492 0.86 ACE (0.68) FKBP1AACERENLMNAKDM4E
SCHEMBL3388998 0.85 FKBP1A (0.51) FKBP1AACERENLMNAKDM4E
SCHEMBL12894600 0.85 FKBP1A (0.48) FKBP1AACERENLMNAKDM4E
Hydrochloric Acid SCHEMBL3388993 0.84 FKBP1A (0.50) FKBP1AACERENLMNAKDM4E
Hydrochloric Acid SCHEMBL7361206 0.84 FKBP1A (0.50) FKBP1AACERENLMNAKDM4E
SCHEMBL4633817 0.84 FKBP1A (0.52) FKBP1AACERENLMNAKDM4E
SCHEMBL13981344 0.84 FKBP1A (0.59) FKBP1AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110269717-A1 NEUROGENESIS BY MODULATING ANGIOTENSIN BRAINCELLS INC. (US) 2011-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269717-A1 NEUROGENESIS BY MODULATING ANGIOTENSIN NGF, DCX, BDNF FKBP1A 1111/4885ACE 6/4885REN 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.