SCHEMBL3389357

SCHEMBL3389357

COC(C)/C=N/C(=O)OC(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.32
CA12 O43570 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14897959 0.82 CA1 (0.32) DGAT1
SCHEMBL15481086 0.82 CA1 (0.32) DGAT1
SCHEMBL23030404 0.77 MEN1 (0.32)
SCHEMBL22096538 0.76 CA1 (0.32)
SCHEMBL24046046 0.74 CTSK (0.32)
SCHEMBL29846523 0.73 CTSK (0.33) CA12CA14
SCHEMBL5768258 0.73 CTSK (0.46)
SCHEMBL19533132 0.70 CYP2D6 (0.38)
SCHEMBL27640595 0.70 NOS1 (0.33)
SCHEMBL27668493 0.70 CTSK (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012002577-A1 NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF 富士フイルム株式会社 (JP) 2012-01-05 WO disclosed