SCHEMBL3389388

SCHEMBL3389388

CCCC[Si](N)(CCCC)CCCC

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
LMNA P02545 1/20 0.40
THRB P10828 1/20 0.38
DNM1 Q05193 8/20 0.35
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
EPHX1 P07099 1/20 0.35
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
OPRM1 P35372 1/20 0.30
EPHX2 P34913 1/20 0.30
SLC22A2 O15244 1/20 0.30
SLC22A1 O15245 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28665588 0.94 TSHR (0.35) TSHRLMNATHRBDNM1ALDH1A1
SCHEMBL28470012 0.94 TSHR (0.41) TSHRLMNATHRBDNM1ALDH1A1
SCHEMBL28669348 0.91 TSHR (0.47) TSHRLMNATHRBDNM1ALDH1A1
SCHEMBL4621265 0.87 TSHR (0.50) TSHRLMNATHRBDNM1ALDH1A1
SCHEMBL6280788 0.87 TSHR (0.35) TSHRLMNATHRBDNM1ALDH1A1
SCHEMBL38654149 0.87 TSHR (0.35) TSHRLMNATHRBDNM1ALDH1A1
SCHEMBL28658915 0.84 TSHR (0.39) TSHRLMNATHRBDNM1ALDH1A1
SCHEMBL5353699 0.79 TSHR (0.40) TSHRLMNATHRBDNM1ALDH1A1
SCHEMBL19031021 0.79
SCHEMBL842545 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930869-A Auxiliary agent for olefin polymerization, olefin catalyst system, prepolymerized catalyst composition and olefin polymerization method 中国石油化工股份有限公司 2025-05-06 CN claimed
CN-119930872-A Catalyst system, prepolymerized catalyst composition and olefin polymerization process 中国石油化工股份有限公司 2025-05-06 CN claimed
CN-113754802-B Catalyst system for olefin polymerization reaction and prepolymerization catalyst composition 中国石油化工股份有限公司 2023-03-31 CN claimed
CN-113754802-A Catalyst system for olefin polymerization reaction and prepolymerization catalyst composition 中国石油化工股份有限公司 2021-12-07 CN claimed
CN-111234062-A Catalyst system for olefin polymerization and use thereof 中国石油化工股份有限公司 2020-06-05 CN claimed
CN-110938163-A Catalyst system for olefin polymerization and prepolymerized catalyst composition and use thereof 中国石油化工股份有限公司 2020-03-31 CN claimed
CN-110938162-A Catalyst system for olefin polymerization and prepolymerized catalyst composition and use thereof 中国石油化工股份有限公司 2020-03-31 CN claimed
CN-110938157-A Catalyst system for olefin polymerization and prepolymerized catalyst composition and use thereof 中国石油化工股份有限公司 2020-03-31 CN claimed
US-8202928-B2 Amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof CONTINENTAL AUTOMOTIVE SYSTEMS, INC (US) 2012-06-19 US claimed
US-20100038859-A1 METHOD OF PREPARING AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US claimed
US-20100038856-A1 AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US claimed
US-20260132224-A1 METHOD FOR PRODUCING SILYLATED CELLULOSE DOW GLOBAL TECH LLC (US) 2026-05-14 US disclosed
US-20260132225-A1 METHOD FOR PRODUCING POWDERED SILYLATED CELLULOSE DOW SILICONES CORP (US) 2026-05-14 US disclosed
US-20260018421-A1 SUBSTRATE PROCESSING METHOD, AND SUBSTRATE MANUFACTURING METHOD CENTRAL GLASS CO LTD (JP) 2026-01-15 US disclosed
US-20250343040-A1 SUBSTRATE PROCESSING METHOD AND SUBSTRATE PRODUCTION METHOD CENTRAL GLASS CO LTD (JP) 2025-11-06 US disclosed
EP-0391850-B1 Unsaturated amino-dicarboxylic acid derivatives CIBA GEIGY AG (CH) 1994-09-28 EP disclosed
US-5134134-A Unsaturated aminodicarboxylic acid derivatives CIBA-GEIGY CORPORATION (US) 1992-07-28 US disclosed
EP-0391850-A2 Unsaturated amino-dicarboxylic acid derivatives CIBA-GEIGY AG (CH) 1990-10-10 EP disclosed
US-4434283-A Polysiloxane molding compositions BAYER AKTIENGESELLSCHAFT (DE) 1984-02-28 US disclosed
EP-0022976-A1 Polysiloxane moulding compositions BAYER AG (DE) 1981-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260018421-A1 SUBSTRATE PROCESSING METHOD, AND SUBSTRATE MANUFACTURING METHOD ESPL1, SMS, SGMS1 TSHR 2961/4885LMNA 115/4885THRB 2882/4885
US-20260132224-A1 METHOD FOR PRODUCING SILYLATED CELLULOSE GSK3B, GSK3A, FOXM1 TSHR 4865/4885LMNA 111/4885THRB 4838/4885
US-20260132225-A1 METHOD FOR PRODUCING POWDERED SILYLATED CELLULOSE GSK3B, GSK3A, MTOR TSHR 4705/4885LMNA 400/4885THRB 4678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.