Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28669348 | 0.97 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL28470012 | 0.94 | TSHR (0.41) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL28658915 | 0.91 | TSHR (0.39) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL3389388 | 0.87 | TSHR (0.40) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL29449237 | 0.81 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL29449222 | 0.81 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL29449227 | 0.81 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL29449269 | 0.81 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL29449232 | 0.81 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL14859089 | 0.81 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881955-A1 | BIS-AMINATION OF ARYL HALIDES | Boehringer Ingelheim International GmbH (DE) | 2008-01-30 | — | — | EP | claimed |
| WO-2006124283-A1 | BIS-AMINATION OF ARYL HALIDES | BOEHRINGER INGELHEIM INTERNATIONAL, GMBH (DE) | 2006-11-23 | — | — | WO | claimed |
| US-20060258888-A1 | Bis-Amination of Aryl Halides | BOEHRINGER INGELHEIM INTERNATIONAL, GMBH (DE) | 2006-11-16 | — | — | US | claimed |
| WO-2014206863-A1 | POLYMERS BASED ON FUSED DIKETOPYRROLOPYRROLES | BASF SE (DE) | 2014-12-31 | — | — | WO | disclosed |
| EP-1624851-B1 | HAIR CARE APPLICATIONS OF EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES WITH NITROGEN ATOMS | DOW CORNING (US) | 2014-05-28 | — | — | EP | disclosed |
| US-7902293-B2 | Method of preparing emulsions containing elastomeric silanes and siloxanes having quaternary ammonium groups | DOW CORNING CORPORATION (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1625132-B1 | METHOD OF PREPARING EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES HAVING QUATERNARY AMMONIUM GROUPS | DOW CORNING (US) | 2008-08-13 | — | — | EP | disclosed |
| US-20060269506-A1 | Personal care applications of emulsions containing elastomeric silanes and siloxanes with nitrogen atoms | DOW CORNING CORPORATION (US) | 2006-11-30 | — | — | US | disclosed |
| US-20060193805-A1 | Method of preparing emulsions containing elastomeric silanes and siloxanes having quaternary ammonium groups | DOW SILICONES CORPORATION | 2006-08-31 | — | — | US | disclosed |
| EP-1426398-B1 | Method of making emulsion containing quaternary ammonium functional silanes and siloxanes | DOW CORNING (US) | 2006-07-05 | — | — | EP | disclosed |
| EP-1625132-A1 | METHOD OF PREPARING EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES HAVING QUATERNARY AMMONIUM GROUPS | Dow Corning Corporation (US) | 2006-02-15 | — | — | EP | disclosed |
| US-6452060-B2 | BY REACTING AN ALLYL COMPOUND HAVING A LEAVING GROUP WITH A NON-NUCLEOPHILIC STRONG BASE IN AN INERT SOLVENT IN THE PRESENCE OF A CATALYTIC AMOUNT OF A NON-NUCLEOPHILIC, WEAKER BASE; HIGH YIELD, CATALYST SELECTIVITY | ROHM AND HAAS COMPANY | 2002-09-17 | — | — | US | disclosed |
| US-20020043730-A1 | Continuous process for the preparation of encapsulated cyclopropenes | AGROFRESH, INC. | 2002-04-18 | — | — | US | disclosed |
| US-20010051756-A1 | Method to prepare cyclopropenes | AGROFRESH, INC. | 2001-12-13 | — | — | US | disclosed |
| EP-1146028-A1 | A method to prepare cyclopropenes | ROHM AND HAAS COMPANY (US) | 2001-10-17 | — | — | EP | disclosed |
| EP-0610038-B1 | Preparation of alkylsilyl nitrile | SIVENTO INC (US) | 2001-08-29 | — | — | EP | disclosed |
| CN-1042336-C | Preparation of trialkylsilyl nitrile | HULS AMERICA INC (US) | 1999-03-03 | — | — | CN | disclosed |
| EP-0759439-A2 | Synthesis of silylated cyanohydrins | HÜLS AMERICA INC. (US) | 1997-02-26 | — | — | EP | disclosed |
| EP-0610038-A1 | Preparation of alkylsilyl nitrile | HÜLS AMERICA INC. (US) | 1994-08-10 | — | — | EP | disclosed |
| US-5258534-A | Preparation of trialkylsilyl nitrile | HULS AMERICA, INC. (US) | 1993-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010051756-A1 | Method to prepare cyclopropenes | CYP11A1, CYP11B2, CYCS | TSHR 4223/4885THRB 4819/4885DNM1 155/4885 |
| US-20020043730-A1 | Continuous process for the preparation of encapsulated cyclopropenes | AGPS, CYCS, PDIA6 | TSHR 4596/4885THRB 4871/4885DNM1 1827/4885 |
| US-20060258888-A1 | Bis-Amination of Aryl Halides | ABL1, AOC2, AADAC | TSHR 926/4885THRB 696/4885DNM1 4063/4885 |
| US-20060193805-A1 | Method of preparing emulsions containing elastomeric silanes and siloxanes having quaternary ammonium groups | COPE, ITCH, CUTA | TSHR 4691/4885THRB 3846/4885DNM1 3509/4885 |
| US-20060269506-A1 | Personal care applications of emulsions containing elastomeric silanes and siloxanes with nitrogen atoms | CUTA, POLR1C, ITCH | TSHR 4481/4885THRB 3271/4885DNM1 3678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.