SCHEMBL3389390

SCHEMBL3389390

CCCCN[SiH](NCCCC)NCCCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.45
ALDH1A1 P00352 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
ADH1B P00325 2/20 0.39
ADH1C P00326 2/20 0.39
ADH1A P07327 2/20 0.39
ADH7 P40394 2/20 0.39
CA12 O43570 1/20 0.39
CA7 P43166 1/20 0.39
CA14 Q9ULX7 1/20 0.39
LMNA P02545 1/20 0.38
EPHX1 P07099 6/20 0.36
THRB P10828 1/20 0.35
ALOX15 P16050 1/20 0.35
ACHE P22303 1/20 0.32
MMP2 P08253 1/20 0.32
ADH4 P08319 1/20 0.32
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28446156 0.88 EPHX1 (0.52) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL10630592 0.88 EPHX1 (0.52) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL521830 0.79 ADH1B (0.33) TSHRALDH1A1CA1ADH1BADH1A
SCHEMBL8860884 0.78
SCHEMBL9636691 0.78 ADH1B (0.43) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL10024711 0.75 TSHR (0.41) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL21828554 0.75 TSHR (0.41) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL16396823 0.71 TSHR (0.38) TSHRALDH1A1CA1CA2ADH1B
SCHEMBL2532 0.67
SCHEMBL308609 0.67 TSHR (0.53) TSHRALDH1A1CA1CA2ADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8202928-B2 Amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof CONTINENTAL AUTOMOTIVE SYSTEMS, INC (US) 2012-06-19 US claimed
US-20100038859-A1 METHOD OF PREPARING AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US claimed
US-20100038856-A1 AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US claimed
CN-119776805-A Modified silicon nitride film and preparation method and application thereof 大连恒坤新材料有限公司 2025-04-08 CN disclosed
US-20240026527-A1 METHOD OF DEPOSITING SILICON BASED DIELECTRIC FILM APPLIED MATERIALS, INC. (US) 2024-01-25 US disclosed
CN-112435934-A Packaging method 朗姆研究公司 2021-03-02 CN disclosed
CN-107346745-B Packaging method 朗姆研究公司 2020-10-16 CN disclosed
US-20170323785-A1 METHOD TO DEPOSIT CONFORMAL AND LOW WET ETCH RATE ENCAPSULATION LAYER USING PECVD LAM RESEARCH CORPORATION 2017-11-09 US disclosed
US-8202928-B2 Amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof CONTINENTAL AUTOMOTIVE SYSTEMS, INC (US) 2012-06-19 US disclosed
US-20100038859-A1 METHOD OF PREPARING AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US disclosed
US-20100038856-A1 AMINE-CURED SILICONE COMPOSITIONS RESISTANT TO HYDROCARBON FLUID AND USES THEREOF TEMIC AUTOMOTIVE OF NORTH AMERICA, INC. (US) 2010-02-18 US disclosed
EP-1165682-B1 RESIN COMPOSITION AND CURED PRODUCT DSM IP ASSETS BV (NL) 2006-07-05 EP disclosed
US-6727334-B2 FOR FORMING COATINGS WITH HIGH HARDNESS, SCRATCH RESISTANCE, LOW CURLING PROPERTIES, ADHESION, AND TRANSPARENCY, AND FINE APPEARANCE ON THE SURFACE OF VARIOUS SUBSTRATES FOR SUCH AS PLASTICS DSM N.V. (NL) 2004-04-27 US disclosed
US-20020058737-A1 Resin composition and cured product JSR CORPORATION (JP) 2002-05-16 US disclosed
US-4434283-A Polysiloxane molding compositions BAYER AKTIENGESELLSCHAFT (DE) 1984-02-28 US disclosed
US-4302571-A TERMINATED AT BOTH ENDS WITH SILANOIC HYDROXY GROUPS AND AN ORGANOSILANE OR ORGANOPOLYSILOXANE WITH HYDROLYZABLE GROUPS TO SERVE AS CROSSLINKING AGENTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1981-11-24 US disclosed
EP-0022976-A1 Polysiloxane moulding compositions BAYER AG (DE) 1981-01-28 EP disclosed
US-4073825-A FIRE RETARDANT, NONSMOKING ARMSTRONG CORK COMPANY (US) 1978-02-14 US disclosed
US-4026839-A SILICONE RUBBER BLENDS AND FOAMS THEREFROMFIRE RESISTANT, NONSMOKING ARMSTRONG CORK COMPANY (US) 1977-05-31 US disclosed