SCHEMBL3389582

SCHEMBL3389582

CC(=O)C/C(C)=N\CC/N=C(\C)CC(C)=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 1.00
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 1/20 0.35
KDM6B O15054 1/20 0.35
KDM5C P41229 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL348034 1.00 HTT (1.00) HTTMGAMGAASIMGAM2
SCHEMBL351512 1.00 HTT (1.00) HTTMGAMGAASIMGAM2
SCHEMBL348035 1.00 HTT (1.00) HTTMGAMGAASIMGAM2
SCHEMBL7746127 0.97 HTT (0.94) HTTMGAMGAASIMGAM2
SCHEMBL348060 0.87 HTT (0.76) HTTMGAMGAASIMGAM2
SCHEMBL346894 0.87 HTT (0.76) HTTMGAMGAASIMGAM2
SCHEMBL346893 0.87 HTT (0.76) HTTMGAMGAASIMGAM2
SCHEMBL9959054 0.87 HTT (0.76) HTTMGAMGAASIMGAM2
SCHEMBL16627957 0.87 HTT (0.76) HTTMGAMGAASIMGAM2
SCHEMBL348061 0.87 HTT (0.76) HTTMGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1325777-B1 ABSORBENTS AND PROCESS FOR PRODUCING THE SAME, ABSORBABLE CONSTRUCTS AND ABSORBABLE ARTICLES SANYO CHEMICAL IND LTD (JP) 2010-12-22 EP disclosed
US-7087669-B2 Absorbents and process for producing the same, absorbable constructs and absorbable articles SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-08 US disclosed
US-6951911-B2 Cross-linked polymer and process for producing the same, absorptive structure and absorptive article SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2005-10-04 US disclosed
US-20040024104-A1 Absorbents and process for producing the same, absorbable constructs and absorbable articles SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2004-02-05 US disclosed
EP-1325777-A1 ABSORBENTS AND PROCESS FOR PRODUCING THE SAME, ABSORBABLE CONSTRUCTS AND ABSORBABLE ARTICLES SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2003-07-09 EP disclosed
US-20030078349-A1 For use in paper diaper, a physiological napkin, a pad, a paper towel TAGAWA DAISUKE (JP) 2003-04-24 US disclosed
EP-1275669-A1 CROSSLINKED POLYMER, PROCESS FOR PRODUCING THE SAME, ABSORBENT STRUCTURE, AND ABSORBENT ARTICLE SANYO CHEMICAL INDUSTRIES, Ltd. (JP) 2003-01-15 EP disclosed