SCHEMBL348035

SCHEMBL348035

CC(=O)CC(C)=NCCN=C(C)CC(C)=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 1.00
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 1/20 0.35
KDM6B O15054 1/20 0.35
KDM5C P41229 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL348034 1.00 HTT (1.00) HTTMGAMGAASIMGAM2
SCHEMBL3389582 1.00 HTT (1.00) HTTMGAMGAASIMGAM2
SCHEMBL351512 1.00 HTT (1.00) HTTMGAMGAASIMGAM2
SCHEMBL7746127 0.97 HTT (0.94) HTTMGAMGAASIMGAM2
SCHEMBL348060 0.87 HTT (0.76) HTTMGAMGAASIMGAM2
SCHEMBL346894 0.87 HTT (0.76) HTTMGAMGAASIMGAM2
SCHEMBL346893 0.87 HTT (0.76) HTTMGAMGAASIMGAM2
SCHEMBL9959054 0.87 HTT (0.76) HTTMGAMGAASIMGAM2
SCHEMBL16627957 0.87 HTT (0.76) HTTMGAMGAASIMGAM2
SCHEMBL348061 0.87 HTT (0.76) HTTMGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4460682-A NONDIFFUSING COBALT(III) COMPLEX KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-07-17 US claimed
JP-8259528-A None JP disclosed
EP-3020766-B1 CURING ACCELERATOR FOR OXIDATION POLYMERIZED UNSATURATED RESIN, PRINTING INK, AND COATING MATERIAL DAINIPPON INK & CHEMICALS (JP) 2019-11-20 EP disclosed
US-9896603-B2 Curing accelerator for oxidative polymerization-type unsaturated resin, printing ink, and coating material DIC CORPORATION (JP) 2018-02-20 US disclosed
EP-2468801-B1 PROCESS FOR PRODUCING THERMOPLASTIC RESIN COMPOSITION, MOLDED OBJECT, AND LUMINESCENT OBJECT MITSUBISHI RAYON CO (JP) 2017-04-26 EP disclosed
US-20160152867-A1 CURING ACCELERATOR FOR OXIDATIVE POLYMERIZATION-TYPE UNSATURATED RESIN, PRINTING INK, AND COATING MATERIAL DIC CORPORATION (JP) 2016-06-02 US disclosed
EP-3020766-A1 CURING ACCELERATOR FOR OXIDATION POLYMERIZED UNSATURATED RESIN, PRINTING INK, AND COATING MATERIAL DIC Corporation (JP) 2016-05-18 EP disclosed
WO-2016033156-A1 IRON-CATALYZED OXIDATIVE POLYMERIZATION OF PHENOLS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-03-03 WO disclosed
US-8889785-B2 Production method of thermoplastic resin composition, molded body, and light emission body MITSUBISHI RAYON CO., LTD. (JP) 2014-11-18 US disclosed
US-20120214922-A1 PRODUCTION METHOD OF THERMOPLASTIC RESIN COMPOSITION, MOLDED BODY, AND LIGHT EMISSION BODY MITSUBISHI RAYON CO., LTD. (JP) 2012-08-23 US disclosed
US-6344516-B1 TRANSITION METAL COMPLEX CATALYST, OXIDATATIVE POLYMERIZATION OF PHENOL-CONTAINING VEGETABLE OIL NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2002-02-05 US disclosed
EP-1114836-A1 RESIN COMPOSITION AND PROCESS FOR PRODUCING THE SAME Japan as represented by Secretary of Agency of Industrial Science and Technology (JP) 2001-07-11 EP disclosed
JP-H08259528-A PRODUCTION OF ARYLALKYLHYDROPEROXIDE COMPOUNDS MITSUI PETROCHEM IND LTD 1996-10-08 JP disclosed
EP-0196783-B1 COBALT(II) CHELATES AS CHAIN TRANSFER AGENTS IN FREE RADICAL POLYMERIZATIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-11-23 EP disclosed
US-4680352-A Cobalt (II) chelates as chain transfer agents in free radical polymerizations E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-07-14 US disclosed
EP-0196783-A1 Cobalt(II) chelates as chain transfer agents in free radical polymerizations E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-10-08 EP disclosed
EP-0094160-B1 VINYL CHLORIDE POLYMERISATION PROCESS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-07-16 EP disclosed
US-4539381-A REDUCTION OF CHELATE TO ACTIVE FORM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-09-03 US disclosed
US-4460682-A NONDIFFUSING COBALT(III) COMPLEX KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-07-17 US disclosed
EP-0094160-A1 Vinyl chloride polymerisation process IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-11-16 EP disclosed