SCHEMBL351512

SCHEMBL351512

CC(=O)C/C(C)=N/CC/N=C(\C)CC(C)=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 1.00
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 1/20 0.35
KDM6B O15054 1/20 0.35
KDM5C P41229 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL348034 1.00 HTT (1.00) HTTMGAMGAASIMGAM2
SCHEMBL3389582 1.00 HTT (1.00) HTTMGAMGAASIMGAM2
SCHEMBL348035 1.00 HTT (1.00) HTTMGAMGAASIMGAM2
SCHEMBL7746127 0.97 HTT (0.94) HTTMGAMGAASIMGAM2
SCHEMBL348060 0.87 HTT (0.76) HTTMGAMGAASIMGAM2
SCHEMBL346894 0.87 HTT (0.76) HTTMGAMGAASIMGAM2
SCHEMBL346893 0.87 HTT (0.76) HTTMGAMGAASIMGAM2
SCHEMBL9959054 0.87 HTT (0.76) HTTMGAMGAASIMGAM2
SCHEMBL16627957 0.87 HTT (0.76) HTTMGAMGAASIMGAM2
SCHEMBL348061 0.87 HTT (0.76) HTTMGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220127293-A1 LIQUID METAL COMPLEX HAVING OXYGEN-ABSORBING ABILITY SHARP KABUSHIKI KAISHA (JP) 2022-04-28 US claimed
US-7896935-B2 Process of conducting reactions or separation in a microchannel with internal fin support for catalyst or sorption medium VELOCYS, INC. (US) 2011-03-01 US claimed
EP-2210268-A1 NOVEL CHEMISTRY USED IN BIOSENSORS Ohmx Corporation (US) 2010-07-28 EP claimed
WO-2009052436-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2009-04-23 WO claimed
JP-2007534457-A 2007-11-29 JP claimed
US-20070140955-A1 MICROCHANNEL WITH INTERNAL FIN SUPPORT FOR CATALYST OR SORPTION MEDIUM TONKOVICH ANNA L 2007-06-21 US claimed
US-7220390-B2 Microchannel with internal fin support for catalyst or sorption medium VELOCYS, INC. (US) 2007-05-22 US claimed
EP-1631376-A1 MICROCHANNEL WITH INTERNAL FIN SUPPORT FOR CATALYST OR SUPPORT MEDIUM Velocys, Inc. (US) 2006-03-08 EP claimed
EP-1562688-A1 PROCESS FOR SEPARATING A FLUID COMPONENT FROM A FLUID MIXTURE BY SORPTION USING MICROCHANNEL PROCESS TECHNOLOGY Velocys, Inc. (US) 2005-08-17 EP claimed
WO-2004103550-A1 MICROCHANNEL WITH INTERNAL FIN SUPPORT FOR CATALYST OR SUPPORT MEDIUM VELOCYS INC. (US) 2004-12-02 WO claimed
US-20040228781-A1 chemical reactors having microstructure passageways, catalysts supports, absorber materials and heat exchangers VELOCYS, INC. 2004-11-18 US claimed
WO-2004041414-A1 PROCESS FOR SEPARATING A FLUID COMPONENT FROM A FLUID MIXTURE BY SORPTION USING MICROCHANNEL PROCESS TECHNOLOGY VELOCYS, INC. (US) 2004-05-21 WO claimed
US-6652627-B1 Process for separating a fluid component from a fluid mixture using microchannel process technology VELOCYS, INC. 2003-11-25 US claimed
CN-115605479-B Pyridopyrimidine derivatives, preparation method thereof and application thereof in medicines 江苏恒瑞医药股份有限公司 2024-05-14 CN disclosed
US-20230422602-A1 CERIUM-ETHYLENEDIAMINE KETONE-TYPE AND CERIUM-SALEN-TYPE COMPLEXES AND USE THEREOF IN ORGANIC ELECTRONICS Credoxys GmbH (DE) 2023-12-28 US disclosed
EP-4244910-A1 CERIUM-ETHYLENEDIAMINE KETONE-TYPE AND CERIUM-SALEN-TYPE COMPLEXES AND USE THEREOF IN ORGANIC ELECTRONICS Credoxys GmbH c/o Institut for Applied Physics (DE) 2023-09-20 EP disclosed
EP-0249614-A1 OLIGOMERIZATION PROCESS. COMMW SCIENT IND RES ORG (AU) 1987-12-23 EP disclosed
WO-1987003605-A1 OLIGOMERIZATION PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) 1987-06-18 WO disclosed
US-4338291-A Process for producing hydrogen with viologen cation radical using metal complex of macrocyclic polydentate compound as catalyst RIKAGAKU KENKYUSHO (JP) 1982-07-06 US disclosed
US-4104466-A ACRYLIC POLYMER LIGANDS, ADSORPTION AND DESORPTION OF OXYGEN Tsuchida, Eishun (JP) 1978-08-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127293-A1 LIQUID METAL COMPLEX HAVING OXYGEN-ABSORBING ABILITY OTC, CA9, SLC39A14 HTT 4795/4885MGAM 1118/4885GAA 2415/4885
US-20230422602-A1 CERIUM-ETHYLENEDIAMINE KETONE-TYPE AND CERIUM-SALEN-TYPE COMPLEXES AND USE THEREOF IN ORGANIC ELECTRONICS KCNH3, KCNE1, PDHA1 HTT 1590/4885MGAM 3943/4885GAA 976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.