Acetic Acid

Acetic Acid

SCHEMBL3389770

CC(=O)O.CC(O)CCCCO.O=CO

nearest known ligand 0.38

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
MAPT P10636 1/20 0.38
PSMD14 O00487 2/20 0.33
PLA2G1B P04054 2/20 0.33
MMP2 P08253 2/20 0.33
ATG4B Q9Y4P1 2/20 0.33
HSP90AA1 P07900 1/20 0.33
RAD52 P43351 1/20 0.33
GPR84 Q9NQS5 4/20 0.32
FFAR1 O14842 2/20 0.32
FFAR4 Q5NUL3 1/20 0.32
PTPN1 P18031 1/20 0.31
AKR1B1 P15121 1/20 0.30
CAMK2A Q9UQM7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL3392029 0.94 ALDH1A1 (0.35) ALDH1A1MAPTPSMD14PLA2G1BMMP2
1,3-Butanediol SCHEMBL2160926 0.85 ALDH1A1 (0.34) ALDH1A1MAPTAKR1B1
Acetic Acid SCHEMBL27692003 0.85 ALDH1A1 (0.37) ALDH1A1MAPTGPR84FFAR1FFAR4
1,4-Butanediol SCHEMBL2161930 0.82 GPR84 (0.43) ALDH1A1GPR84FFAR1FFAR4CAMK2A
Acetic Acid SCHEMBL3391441 0.82 TSHR (0.37) ALDH1A1GPR84FFAR1FFAR4PTPN1
SCHEMBL27691670 0.81 ALDH1A1 (0.36) ALDH1A1MAPTGPR84FFAR1FFAR4
1,6-Hexanediol SCHEMBL3387365 0.80 GPR84 (0.48) ALDH1A1GPR84FFAR1FFAR4CAMK2A
1,5-Pentanediol SCHEMBL3391585 0.80 GPR84 (0.48) ALDH1A1GPR84FFAR1FFAR4CAMK2A
Methacrylic Acid SCHEMBL1898443 0.80 ALDH1A1 (0.34) ALDH1A1MAPTGPR84FFAR1FFAR4
Methacrylic Acid SCHEMBL9779454 0.80 ALDH1A1 (0.34) ALDH1A1MAPTGPR84FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1729365-B1 NON-AQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING THE SAME UBE INDUSTRIES (JP) 2010-12-22 EP disclosed
US-20080241704-A1 Nonaqueous Electrolyte Solution and Lithium Secondary Battery Using Same UBE INDUSTRIES, LTD (JP) 2008-10-02 US disclosed
EP-1729365-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY USING SAME Ube Industries, Ltd. (JP) 2006-12-06 EP disclosed