Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.55 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | GYS1 | P13807 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3267568 | 0.84 | AKT2 (0.56) | IKBKBMAP3K14MAPTNPSR1MAPK1 | |
| SCHEMBL3261336 | 0.83 | HSP90AA1 (0.48) | IKBKBMAP3K14MAPTNPSR1ALOX12 | |
| SCHEMBL3261526 | 0.83 | LRRK2 (0.51) | IKBKBMAP3K14KMT2ATDP1LRRK2 | |
| SCHEMBL3263313 | 0.75 | ALK (0.47) | CYP1A2CYP3A4CYP2C19TDP1LRRK2 | |
| SCHEMBL24962586 | 0.74 | IKBKB (0.68) | IKBKBMAP3K14MAPTNPSR1ALOX12 | |
| SCHEMBL3262839 | 0.73 | MAPT (0.49) | MAPTGAAKDM4EATMLMNA | |
| SCHEMBL24962583 | 0.71 | IKBKB (0.64) | IKBKBMAP3K14MAPTNPSR1ALOX12 | |
| SCHEMBL3262693 | 0.71 | ATM (0.42) | IKBKBMAP3K14MAPTKMT2AHTT | |
| SCHEMBL3259645 | 0.69 | KMT2A (0.50) | MAPTNPSR1ALOX12MAPK1KMT2A | |
| SCHEMBL24964988 | 0.68 | IKBKB (0.58) | IKBKBMAP3K14MAPTNPSR1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |