Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 3/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261526 | 0.85 | LRRK2 (0.51) | AKT2CHEK1KMT2ALRRK2HSD17B10 | |
| SCHEMBL3390214 | 0.84 | IKBKB (0.55) | AKT2CHEK1KMT2ALRRK2TP53 | |
| SCHEMBL3263313 | 0.83 | ALK (0.47) | AKT2CHEK1LRRK2IKBKELMNA | |
| SCHEMBL3261336 | 0.83 | HSP90AA1 (0.48) | KMT2ALRRK2TP53HSD17B10NPSR1 | |
| SCHEMBL3262839 | 0.81 | MAPT (0.49) | TP53KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL3261073 | 0.78 | L3MBTL1 (0.55) | AKT2CHEK1KMT2ALRRK2NPSR1 | |
| SCHEMBL3259645 | 0.77 | KMT2A (0.50) | KMT2ALRRK2TP53HSD17B10NPSR1 | |
| SCHEMBL3260006 | 0.77 | CHEK1 (0.56) | AKT2CHEK1KMT2ALRRK2TP53 | |
| SCHEMBL3262752 | 0.73 | SLC5A2 (0.49) | KMT2ALRRK2HSD17B10MEN1POLB | |
| SCHEMBL9048116 | 0.73 | AKT2 (0.66) | AKT2CHEK1KMT2ATP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |