SCHEMBL338153

SCHEMBL338153

CCOC(=O)c1cccc(-c2ccc(C(=O)O)c(C(=O)O)c2)c1C(=O)OCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
PTPN1 P18031 6/20 0.47
PTPRC P08575 2/20 0.47
PTPN2 P17706 2/20 0.47
PTPA Q15257 2/20 0.47
PTPRF P10586 1/20 0.47
MAPT P10636 6/20 0.46
ALOX15 P16050 3/20 0.46
CYP1A2 P05177 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
USP2 O75604 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
MAPK10 P53779 1/20 0.46
PTK2B Q14289 1/20 0.46
NCOA1 Q15788 1/20 0.46
NCOA3 Q9Y6Q9 1/20 0.46
CA12 O43570 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339060 0.96 PTPN1 (0.48) TSHRPTPN1PTPRCPTPN2PTPA
SCHEMBL3869093 0.83 TSHR (0.61) TSHRPTPN1PTPRCPTPN2PTPA
SCHEMBL338971 0.82 SLC6A3 (0.50) TSHRPTPRCMAPTMEN1KMT2A
SCHEMBL5572324 0.82 PTPN1 (0.55) TSHRPTPN1PTPRCPTPN2PTPA
Ether SCHEMBL10413640 0.81 PTPN11 (0.44) PTPN1PTPRCPTPN2PTPAPTPRF
SCHEMBL1346651 0.80 MCL1 (0.42) ALOX15KMT2AALDH1A1HSD17B10PTPN11
SCHEMBL5886273 0.80 TSHR (0.55) TSHRMAPTALOX15MEN1KMT2A
SCHEMBL337973 0.80 TSHR (0.53) TSHRMAPTALOX15MEN1KMT2A
SCHEMBL27523216 0.80 TSHR (0.63) TSHRMAPTALOX15CYP1A2MEN1
SCHEMBL31121002 0.78 PTPN1 (0.54) TSHRPTPN1PTPRCPTPN2PTPA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1721924-B1 ENDLESS TUBULAR POLYIMIDE FILM GUNZE KK (JP) 2014-12-17 EP disclosed
US-8314204-B2 Endless tubular polyimide film GUNZE LIMITED (JP) 2012-11-20 US disclosed
US-20120040121-A1 ENDLESS TUBULAR POLYIMIDE FILM UBE INDUSTRIES, LTD. (JP) 2012-02-16 US disclosed
US-8097693-B2 Endless tubular polyimide film GUNZE LIMITED (JP) 2012-01-17 US disclosed
US-20070178264-A1 Endless tubular polyimide film GUNZE LIMITED (JP) 2007-08-02 US disclosed
EP-1721924-A1 ENDLESS TUBULAR POLYIMIDE FILM GUNZE LIMITED (JP) 2006-11-15 EP disclosed