SCHEMBL338971

SCHEMBL338971

COC(=O)c1cccc(-c2ccc(C(=O)O)c(C(=O)O)c2)c1C(=O)OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 5/20 0.50
SLC6A4 P31645 3/20 0.50
SLC6A2 P23975 1/20 0.50
BDKRB1 P46663 3/20 0.43
MEN1 O00255 2/20 0.43
MAPT P10636 2/20 0.43
KMT2A Q03164 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
MAPK10 P53779 1/20 0.43
PTK2B Q14289 1/20 0.43
NCOA1 Q15788 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NCOA3 Q9Y6Q9 1/20 0.43
ROCK2 O75116 1/20 0.42
CSF1R P07333 1/20 0.42
KDR P35968 1/20 0.42
FLT3 P36888 1/20 0.42
GSK3A P49840 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339059 0.94 SLC6A3 (0.50) SLC6A3SLC6A4SLC6A2BDKRB1MEN1
SCHEMBL4856223 0.90 SLC6A3 (0.54) SLC6A3SLC6A4SLC6A2BDKRB1MEN1
SCHEMBL1346651 0.84 MCL1 (0.42) SLC6A3SLC6A4SLC6A2KMT2AMCL1
SCHEMBL338153 0.82 TSHR (0.47) MEN1MAPTKMT2ANPSR1TSHR
SCHEMBL69682 0.82 SLC6A3 (0.57) SLC6A3SLC6A4SLC6A2MEN1MAPT
SCHEMBL10425360 0.81 CA12 (0.55) SLC6A3SLC6A4MEN1MAPTKMT2A
SCHEMBL3576571 0.81 CA1 (0.59) SLC6A3SLC6A4SLC6A2MEN1MAPT
SCHEMBL6462555 0.81 MCL1 (0.40) SLC6A3SLC6A4SLC6A2NPSR1MCL1
SCHEMBL339060 0.81 PTPN1 (0.48) MEN1MAPTKMT2ANPSR1TSHR
SCHEMBL1697842 0.80 HNF4A (0.54) SLC6A3SLC6A4SLC6A2MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1721924-B1 ENDLESS TUBULAR POLYIMIDE FILM GUNZE KK (JP) 2014-12-17 EP disclosed
US-8314204-B2 Endless tubular polyimide film GUNZE LIMITED (JP) 2012-11-20 US disclosed
US-20120040121-A1 ENDLESS TUBULAR POLYIMIDE FILM UBE INDUSTRIES, LTD. (JP) 2012-02-16 US disclosed
US-8097693-B2 Endless tubular polyimide film GUNZE LIMITED (JP) 2012-01-17 US disclosed
US-20070178264-A1 Endless tubular polyimide film GUNZE LIMITED (JP) 2007-08-02 US disclosed
EP-1721924-A1 ENDLESS TUBULAR POLYIMIDE FILM GUNZE LIMITED (JP) 2006-11-15 EP disclosed