Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 8/20 | 0.46 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390126 | 0.89 | CLPP (0.45) | CLPPC5AR1DRD4PNMTDRD2 | |
| SCHEMBL3390016 | 0.85 | CLPP (0.45) | CLPPC5AR1DRD4DRD2DRD3 | |
| SCHEMBL3391586 | 0.83 | C5AR1 (0.43) | CLPPC5AR1DRD4DRD2DRD3 | |
| SCHEMBL3385404 | 0.82 | C5AR1 (0.48) | CLPPC5AR1DRD4PNMTSIGMAR1 | |
| SCHEMBL17156366 | 0.74 | HTT (0.43) | CLPPC5AR1DRD4DRD2DRD3 | |
| SCHEMBL31414261 | 0.71 | ADORA1 (0.47) | — | |
| SCHEMBL3391569 | 0.71 | ACHE (0.49) | C5AR1DRD4PNMTDRD2DRD3 | |
| SCHEMBL10657990 | 0.71 | CHRM3 (0.57) | C5AR1DRD4PNMTDRD2DRD3 | |
| SCHEMBL31414250 | 0.69 | KMT2A (0.47) | CLPP | |
| SCHEMBL3258869 | 0.69 | HTT (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |