Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.39 |
| ▸ | BCL2A1 | Q16548 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390932 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ARAB9AHDAC1 | |
| SCHEMBL3389942 | 0.86 | S1PR1 (0.35) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL3389938 | 0.86 | S1PR1 (0.35) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL3390368 | 0.84 | CYSLTR2 (0.40) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL3390377 | 0.84 | CYSLTR2 (0.40) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL3390683 | 0.83 | ITGB2 (0.39) | ALDH1A1MEN1KMT2AHDAC1MAPT | |
| SCHEMBL3390688 | 0.83 | ITGB2 (0.39) | ALDH1A1MEN1KMT2AHDAC1MAPT | |
| SCHEMBL3389697 | 0.81 | HPGD (0.41) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL3389699 | 0.81 | HPGD (0.41) | ALDH1A1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL1710636 | 0.80 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AHDAC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093865-A1 | SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093865-A1 | SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ALDH1A2, MPST, CLN6 | ALDH1A1 314/4885MEN1 4678/4885KMT2A 2843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.