Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | PARL | Q9H300 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13900254 | 1.00 | MAPT (0.44) | MAPTACHEALDH1A1POLBL3MBTL1 | |
| SCHEMBL15944148 | 0.78 | MAPT (0.42) | MAPTALDH1A1MMP3MMP8AKR1C3 | |
| SCHEMBL14821016 | 0.78 | MAPT (0.42) | MAPTALDH1A1MMP3MMP8AKR1C3 | |
| SCHEMBL15940394 | 0.78 | MAPT (0.42) | MAPTALDH1A1MMP3MMP8AKR1C3 | |
| SCHEMBL14821447 | 0.78 | MAPT (0.42) | MAPTALDH1A1MMP3MMP8AKR1C3 | |
| SCHEMBL27721305 | 0.76 | MAPT (0.49) | MAPTACHEALDH1A1L3MBTL1PSIP1 | |
| SCHEMBL13909336 | 0.76 | MAPT (0.35) | MAPTALDH1A1MMP3MMP8AKR1C3 | |
| SCHEMBL23720121 | 0.75 | L3MBTL1 (0.46) | MAPTACHEALDH1A1L3MBTL1PSIP1 | |
| SCHEMBL3392609 | 0.71 | MAPT (0.55) | MAPTACHEALDH1A1POLBL3MBTL1 | |
| SCHEMBL3387151 | 0.70 | MAPT (0.50) | MAPTACHEALDH1A1POLBMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1839653-B9 | THERAPEUTIC AGENT FOR SENSORY DISORDERS | MEIJI DAIRIES CORP (JP) | 2010-12-22 | — | — | EP | disclosed |
| EP-1368013-B1 | CYCLOHEXENONE DERIVATIVE FOR TREATING DIABETIC NEUROPATHY | MEIJI DAIRIES CORP (JP) | 2010-12-22 | — | — | EP | disclosed |
| US-7838565-B2 | Use of cyclohexenone derivatives in the manufacture of a medicament for treating diabetic complications | MEIJI DAIRIES CORPORATION (JP) | 2010-11-23 | — | — | US | disclosed |
| EP-2196200-A1 | Cyclohexenone derivative for treating or preventing hypesthesia or hyperesthesia caused by diabetes | Meiji Dairies Corporation (JP) | 2010-06-16 | — | — | EP | disclosed |
| EP-1839653-B1 | THERAPEUTIC AGENT FOR SENSORY DISORDERS | MEIJI DAIRIES CORP (JP) | 2010-06-09 | — | — | EP | disclosed |
| EP-1322748-B1 | STEM CELL DIFFERENTIATION-INDUCING PROMOTER | MEIJI DAIRIES CORP (JP) | 2009-12-02 | — | — | EP | disclosed |
| US-20090069442-A1 | Therapeutic Agent for Sensory Abnormality | MEIJI CO., LTD (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20080312336-A1 | Preventive and/or Therapeutic Agent for Diabetic Vascular Disorder and Respiratory Disorder | UNIVERSITE DE STRASBOURG (FR) | 2008-12-18 | — | — | US | disclosed |
| EP-1839653-A1 | THERAPEUTIC AGENT FOR SENSORY ABNORMALITY | Meiji Dairies Corporation (JP) | 2007-10-03 | — | — | EP | disclosed |
| US-7166642-B1 | Use of cyclohexenone long-chain alcohol for treating neurodegenerative diseases | MEIJI DAIRIES CORPORATION (JP) | 2007-01-23 | — | — | US | disclosed |
| EP-1322748-A2 | STEM CELL DIFFERENTIATION-INDUCING PROMOTER | Meiji Dairies Corporation (JP) | 2003-07-02 | — | — | EP | disclosed |
| EP-1003706-B1 | CYCLOHEXENONE LONG-CHAIN ALCOHOL AND MEDICAMENT CONTAINING SAME | MEIJI MILK PROD CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| WO-2002066023-A1 | USE OF A CYCLOHEXENONE DERIVATIVES IN THE MANUFACTURE OF A MEDICAMENT FOR TREATING DIABETIC COMPLICATIONS | MEIJI DAIRIES CORPORATION (JP) | 2002-08-29 | — | — | WO | disclosed |
| WO-2002066024-A1 | USE OF CYCLOHEXENONE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT IN THE TREATMENT OF DYSURIA | MEIJI DAIRIES CORPORATION (JP) | 2002-08-29 | — | — | WO | disclosed |
| WO-2002029014-A2 | STEM CELL DIFFERENTIATION-INDUCING PROMOTER | MEIJI DAIRIES CORPORATION (JP) | 2002-04-11 | — | — | WO | disclosed |
| EP-1150667-A1 | CYCLOHEXENONE LONG-CHAIN ALCOHOL FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Meiji Dairies Corporation (JP) | 2001-11-07 | — | — | EP | disclosed |
| US-6228893-B1 | TREATING DEMENTIA | MEIJI MILK PRODUCTS CO., LTD. (JP) | 2001-05-08 | — | — | US | disclosed |
| WO-2000047199-A1 | USE OF A CYCLOHEXENONE LONG-CHAIN ALCOHOL FOR TREATING NEURODEGENERATIVE DISEASES | MEIJI DAIRIES CORPORATION (JP) | 2000-08-17 | — | — | WO | disclosed |
| EP-1003706-A1 | CYCLOHEXENONE LONG-CHAIN ALCOHOL AND MEDICAMENT CONTAINING SAME | MEIJI MILK PRODUCTS COMPANY LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999008987-A1 | CYCLOHEXENONE LONG-CHAIN ALCOHOL AND MEDICAMENT CONTAINING SAME | MEIJI MILK PRODUCTS CO., LTD. (JP) | 1999-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312336-A1 | Preventive and/or Therapeutic Agent for Diabetic Vascular Disorder and Respiratory Disorder | CPT1B, CHRM1, ADRA1D | MAPT 4599/4885ACHE 3586/4885ALDH1A1 416/4885 |
| US-20090069442-A1 | Therapeutic Agent for Sensory Abnormality | PMP22, NGF, HRH1 | MAPT 3594/4885ACHE 651/4885ALDH1A1 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.