Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18065023 | 0.86 | RAB9A (0.42) | ALDH1A1POLBGBA2LMNASMN1; SMN2 | |
| SCHEMBL10084211 | 0.86 | ALDH1A1 (0.48) | CYP3A4MAPTALDH1A1POLBGBA2 | |
| SCHEMBL16758164 | 0.86 | ALDH1A1 (0.48) | CYP3A4MAPTALDH1A1POLBGBA2 | |
| SCHEMBL6819743 | 0.86 | ALDH1A1 (0.48) | CYP3A4MAPTALDH1A1POLBGBA2 | |
| SCHEMBL28819356 | 0.86 | ALDH1A1 (0.48) | CYP3A4MAPTALDH1A1POLBGBA2 | |
| SCHEMBL8141816 | 0.82 | FKBP1A (0.48) | POLBLMNASMN1; SMN2FKBP1ARAB9A | |
| SCHEMBL5727740 | 0.82 | FKBP1A (0.48) | POLBLMNASMN1; SMN2FKBP1ARAB9A | |
| SCHEMBL3656325 | 0.82 | FKBP1A (0.48) | POLBLMNASMN1; SMN2FKBP1ARAB9A | |
| SCHEMBL13374841 | 0.81 | FKBP1A (0.53) | POLBLMNASMN1; SMN2FKBP1ARAB9A | |
| SCHEMBL28383221 | 0.81 | SMN1; SMN2 (0.43) | ALDH1A1POLBGBA2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167492-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | Hanmi Pharm. Co., Ltd. (KR) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008150118-A2 | NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS | HANMI PHARM. CO., LTD. (KR) | 2008-12-11 | — | — | WO | disclosed |