Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL27585670 | 0.94 | — | — | |
| Guanidine SCHEMBL5613752 | 0.93 | — | — | |
| Guanidine SCHEMBL29983942 | 0.93 | — | — | |
| Guanidine SCHEMBL11330173 | 0.93 | — | — | |
| Guanidine SCHEMBL2003 | 0.93 | — | — | |
| Guanidine SCHEMBL165720 | 0.93 | NOS2 (0.42) | — | |
| Guanidine SCHEMBL25310528 | 0.86 | — | — | |
| Guanidine SCHEMBL3310493 | 0.86 | — | — | |
| Guanidine SCHEMBL3349156 | 0.86 | — | — | |
| Guanidine SCHEMBL9110704 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120005340-A | Ageing-resistant acrylate rubber compound and preparation method thereof | 九江杜威橡胶科技有限公司 | 2025-05-16 | — | — | CN | claimed |
| CN-100349887-C | Substituted 4-aryl-4H-pyrrolo [2, 3-H ] chromenes and analogs, pharmaceutical compositions and uses thereof | CYTOVIA INC (US) | 2007-11-21 | — | — | CN | claimed |
| CN-1668609-A | Substituted 4-aryl-4H-pyrrolo[2,3-H]chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA INC (US) | 2005-09-14 | — | — | CN | claimed |
| CN-1509275-A | Metalloproteinase inhibitors | — | 2004-06-30 | — | — | CN | claimed |
| CN-1509276-A | Metalloprotease inhibitors | — | 2004-06-30 | — | — | CN | claimed |
| CN-120344082-A | Tin-lead perovskite solar cell based on guanidine-sulfur passivating agent and preparation method thereof | 四川大学 | 2025-07-18 | — | — | CN | disclosed |
| CN-120005340-A | Ageing-resistant acrylate rubber compound and preparation method thereof | 九江杜威橡胶科技有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-113292540-A | N-fluorenyl benzocarbazole compound with quinoxaline as auxiliary receptor, preparation method and application thereof | 浙江工业大学 | 2021-08-24 | — | — | CN | disclosed |
| WO-2020237781-A1 | METHOD FOR INCREASING CAPTURE RATE OF TRACE NUCLEIC ACID IN CELL-FREE BODY FLUID | 浙江大学 | 2020-12-03 | — | — | WO | disclosed |
| CN-110372719-B | N-fluorenyl benzocarbazole compound, preparation method and application thereof | 浙江工业大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-108997335-B | Pyridino-quinazolinone compound and preparation method and application thereof | 浙江工业大学 | 2020-05-05 | — | — | CN | disclosed |
| CN-107001703-B | Rubber composition, method for producing same, and tire | 株式会社普利司通 | 2019-02-15 | — | — | CN | disclosed |
| CN-1181062-C | 2-phenoxy pyrimidine derivative and its use in treating disease | 陈依军 | 2004-12-22 | — | — | CN | disclosed |
| CN-1509275-A | Metalloproteinase inhibitors | — | 2004-06-30 | — | — | CN | disclosed |
| CN-1509276-A | Metalloprotease inhibitors | — | 2004-06-30 | — | — | CN | disclosed |
| CN-1121854-C | Transdermal device containing polyvinylpyrrolidone as solubility ehancer | NOVEN PHARMA (US) | 2003-09-24 | — | — | CN | disclosed |
| CN-1436490-A | Production process of natural marine organism health food with deep sea clam worm as material | INST ZOOLOGY CAS (CN) | 2003-08-20 | — | — | CN | disclosed |
| CN-1362409-A | 2-phenoxy pyrimidine derivative and its use in treating disease | CHEN YIJUN CN | 2002-08-07 | — | — | CN | disclosed |
| CN-1143318-A | Transdermal device containing polyvinylpyrrolidone as dissolution enhancer | NOVEN PHARMA (US) | 1997-02-19 | — | — | CN | disclosed |
| US-5283333-A | Cyclic compounds for forming complexes with urea, guanidine and amidine derivatives | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1994-02-01 | — | — | US | disclosed |