Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383287 | 0.84 | GSR (0.42) | GSRKMT2ACYP2D6SRCNPSR1 | |
| SCHEMBL2761650 | 0.82 | KMT2A (0.56) | GSRKMT2ALMNAALDH1A1PTGS1 | |
| SCHEMBL10404713 | 0.81 | ATM (0.50) | GSRKMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL359219 | 0.79 | KMT2A (0.44) | GSRKMT2ACYP2D6SRCNPSR1 | |
| SCHEMBL5682414 | 0.79 | GSR (0.41) | GSRCYP2D6SRCLMNAMAPK1 | |
| SCHEMBL10679108 | 0.79 | MMP8 (0.50) | GSRKMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL74691 | 0.79 | SRC (0.48) | GSRCYP2D6SRCCYP1A2LMNA | |
| SCHEMBL3980588 | 0.78 | CES2 (0.41) | GSRCYP2D6SRCLMNAMAPK1 | |
| SCHEMBL11602507 | 0.77 | SRC (0.46) | GSRCYP2D6SRCCYP1A2LMNA | |
| SCHEMBL5692151 | 0.77 | GSR (0.42) | GSRCYP2D6SRCLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039861-A2 | DENDRIMER CONJUGATES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-04-08 | — | — | WO | disclosed |