SCHEMBL383287

SCHEMBL383287

O=C(OO)C(c1ccccc1)[N+](=O)[O-]

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.42
KMT2A Q03164 1/20 0.40
CYP2D6 P10635 2/20 0.38
SRC P12931 2/20 0.38
NPSR1 Q6W5P4 2/20 0.37
CYP1A2 P05177 1/20 0.37
PKM P14618 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 2/20 0.36
MAPK1 P28482 1/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
ALDH1A1 P00352 2/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3391500 0.84 GSR (0.41) GSRKMT2ACYP2D6SRCNPSR1
SCHEMBL2761650 0.84 KMT2A (0.56) GSRKMT2ALMNAALDH1A1PTGS1
SCHEMBL10404713 0.82 ATM (0.50) GSRKMT2ASMN1; SMN2ALDH1A1KDM4E
SCHEMBL10679108 0.81 MMP8 (0.50) GSRKMT2ACYP1A2SMN1; SMN2
SCHEMBL74691 0.80 SRC (0.48) GSRCYP2D6SRCCYP1A2LMNA
SCHEMBL11602507 0.79 SRC (0.46) GSRCYP2D6SRCCYP1A2LMNA
SCHEMBL11602886 0.79 SRC (0.46) GSRCYP2D6SRCCYP1A2LMNA
SCHEMBL5692151 0.79 GSR (0.42) GSRCYP2D6SRCLMNAMAPK1
SCHEMBL887039 0.79 SRC (0.46) GSRCYP2D6SRCCYP1A2LMNA
SCHEMBL1538911 0.79 CES2 (0.43) GSRCYP2D6SRCLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1853426-B1 MULTILAYER STRUCTURES BOREALIS TECH OY (FI) 2015-11-04 EP disclosed
EP-2220133-B1 POLYPROPYLENE COPOLYMER BOREALIS TECH OY (FI) 2012-01-25 EP disclosed
US-20100292410-A1 Polypropylene Copolymer BOREALIS TECHNOLOGY OY (FI) 2010-11-18 US disclosed
US-20100280206-A1 POLYETHYLENE COPOLYMER BOREALIS TECHNOLOGY OY (FI) 2010-11-04 US disclosed
EP-2220133-A1 POLYPROPYLENE COPOLYMER Borealis Technology OY (FI) 2010-08-25 EP disclosed
EP-2215131-A1 POLYETHYLENE COPOLYMER Borealis Technology OY (FI) 2010-08-11 EP disclosed
WO-2009059780-A1 POLYPROPYLENE COPOLYMER BOREALIS TECHNOLOGY OY (FI) 2009-05-14 WO disclosed
WO-2009059781-A1 POLYETHYLENE COPOLYMER BOREALIS TECHNOLOGY OY (FI) 2009-05-14 WO disclosed
EP-2058339-A1 Polyethylene copolymer Borealis Technology OY (FI) 2009-05-13 EP disclosed
EP-2058340-A1 Polypropylene Copolymer Borealis Technology OY (FI) 2009-05-13 EP disclosed
EP-1987949-A1 Packaging Laminate Borealis Technology Oy (FI) 2008-11-05 EP disclosed
EP-1853426-A1 MULTILAYER STRUCTURES Borealis Technology OY (FI) 2007-11-14 EP disclosed
WO-2006079449-A1 MULTILAYER STRUCTURES BOREALIS TECHNOLOGY OY (FI) 2006-08-03 WO disclosed
EP-1683631-A1 Multilayer structures Borealis Technology OY (FI) 2006-07-26 EP disclosed