Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.62 |
| ▸ | BCR | P11274 | 4/20 | 0.62 |
| ▸ | PRKCA | P17252 | 4/20 | 0.62 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | SRC | P12931 | 2/20 | 0.53 |
| ▸ | PRKACA | P17612 | 2/20 | 0.53 |
| ▸ | PRKACG | P22612 | 2/20 | 0.53 |
| ▸ | PRKACB | P22694 | 2/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.44 |
| ▸ | CDK1 | P06493 | 4/20 | 0.44 |
| ▸ | CDK2 | P24941 | 4/20 | 0.44 |
| ▸ | MTOR | P42345 | 3/20 | 0.44 |
| ▸ | SMG1 | Q96Q15 | 2/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837839 | 0.83 | ABL1 (0.61) | ABL1BCRPRKCACSNK2A1EGFR | |
| SCHEMBL2322146 | 0.82 | ABL1 (0.74) | ABL1BCRPRKCACSNK2A1EGFR | |
| SCHEMBL3390712 | 0.82 | ABL1 (0.66) | ABL1BCRPRKCACSNK2A1EGFR | |
| SCHEMBL3510088 | 0.81 | CSNK2A1 (0.70) | ABL1BCRPRKCACSNK2A1EGFR | |
| SCHEMBL3509891 | 0.80 | ABL1 (0.74) | ABL1BCRPRKCACSNK2A1EGFR | |
| SCHEMBL8837826 | 0.80 | CSNK2A1 (0.76) | ABL1BCRPRKCACSNK2A1EGFR | |
| SCHEMBL8837795 | 0.80 | ABL1 (0.80) | ABL1BCRPRKCACSNK2A1EGFR | |
| SCHEMBL3511896 | 0.79 | CSNK2A1 (0.76) | ABL1BCRPRKCACSNK2A1EGFR | |
| SCHEMBL3511553 | 0.79 | CSNK2A1 (0.66) | ABL1BCRPRKCACSNK2A1EGFR | |
| SCHEMBL3511762 | 0.79 | ABL1 (0.73) | ABL1BCRPRKCACSNK2A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294810-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | claimed |
| WO-2010055114-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE SA (FR) | 2010-05-20 | — | — | WO | claimed |
| US-5612340-A | ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-03-18 | — | — | US | claimed |
| EP-0672035-A1 | PYRIMIDINEAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Novartis AG (CH) | 1995-09-20 | — | — | EP | claimed |
| WO-1995009847-A1 | PYRIMIDINEAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | CIBA-GEIGY AG (CH) | 1995-04-13 | — | — | WO | claimed |
| US-20110294810-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | disclosed |
| WO-2010055114-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE SA (FR) | 2010-05-20 | — | — | WO | disclosed |
| US-5612340-A | ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294810-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | PRXL2A, AZI2, PIR | ABL1 801/4885BCR 3173/4885PRKCA 4168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.