Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 17/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391696 | 1.00 | CCR5 (0.50) | CCR5OPRL1OPRM1OPRK1KMT2A | |
| Hydrochloric Acid SCHEMBL3390783 | 0.99 | CCR5 (0.49) | CCR5OPRL1OPRM1OPRK1KMT2A | |
| Hydrochloric Acid SCHEMBL3390786 | 0.99 | CCR5 (0.49) | CCR5OPRL1OPRM1OPRK1KMT2A | |
| SCHEMBL3387185 | 0.88 | OPRL1 (0.56) | CCR5OPRL1OPRM1OPRK1KMT2A | |
| SCHEMBL3387190 | 0.88 | OPRL1 (0.56) | CCR5OPRL1OPRM1OPRK1KMT2A | |
| Hydrochloric Acid SCHEMBL3391692 | 0.87 | OPRL1 (0.55) | CCR5OPRL1OPRM1OPRK1KMT2A | |
| Hydrochloric Acid SCHEMBL3391698 | 0.87 | OPRL1 (0.55) | CCR5OPRL1OPRM1OPRK1KMT2A | |
| SCHEMBL3387158 | 0.85 | CCR5 (0.54) | CCR5 | |
| SCHEMBL3387164 | 0.85 | CCR5 (0.54) | CCR5 | |
| Hydrochloric Acid SCHEMBL3391810 | 0.85 | CCR5 (0.53) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709642-B2 | Spirohydantoin compounds and methods for the modulation of chemokine receptor activity | VIROCHEM PHARMA, INC. (CA) | 2010-05-04 | — | — | US | claimed |