Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.39 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.39 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.38 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391734 | 0.87 | GRIN1 (0.55) | GRIN1GRIN2BEGFRPIN1PKN1 | |
| SCHEMBL9063730 | 0.87 | GRIN1 (0.51) | GRIN1GRIN2BEGFRIMPDH2IMPDH1 | |
| SCHEMBL485969 | 0.84 | GRIN1 (0.43) | GRIN1GRIN2BIMPDH2IMPDH1PIN1 | |
| SCHEMBL7765425 | 0.84 | DDAH1 (0.53) | GRIN1GRIN2BIMPDH2IMPDH1PIN1 | |
| SCHEMBL4889180 | 0.84 | CACNA1H (0.46) | GRIN1GRIN2BIMPDH2IMPDH1PIN1 | |
| SCHEMBL7653718 | 0.84 | TDP1 (0.47) | GRIN1GRIN2BIMPDH2IMPDH1PIN1 | |
| SCHEMBL7655130 | 0.81 | RAD52 (0.50) | GRIN1GRIN2BIMPDH2IMPDH1PIN1 | |
| SCHEMBL12596890 | 0.81 | EGFR (0.42) | EGFRPIN1MEN1KMT2A | |
| SCHEMBL11339364 | 0.81 | TDP1 (0.47) | EGFRMEN1KMT2A | |
| SCHEMBL12940748 | 0.81 | CSNK2A1 (0.45) | EGFRMETAP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954764-B1 | BENZOPYRAN COLORANTS, METHOD OF MANUFACTURE, AND METHOD OF USE | SABIC INNOVATIVE PLASTICS IP (NL) | 2010-12-22 | — | — | EP | disclosed |
| EP-1954764-A2 | BENZOPYRAN COLORANTS, METHOD OF MANUFACTURE, AND METHOD OF USE | General Electric Company (US) | 2008-08-13 | — | — | EP | disclosed |
| US-7351461-B2 | Articles comprising benzopyran colorants, method of manufacture, and method of use | GENERAL ELECTRIC COMPANY (US) | 2008-04-01 | — | — | US | disclosed |
| US-20070238817-A1 | Articles Comprising Benzopyran Colorants, Method Of Manufacture, And Method Of Use | GENERAL ELECTRIC COMPANY (US) | 2007-10-11 | — | — | US | disclosed |
| US-7270772-B2 | Benzopyran colorants, method of manufacture, and method of use | GENERAL ELECTRIC COMPANY (US) | 2007-09-18 | — | — | US | disclosed |
| WO-2007064563-A2 | BENZOPYRAN COLORANTS, METHOD OF MANUFACTURE, AND METHOD OF USE | GENERAL ELECTRIC COMPANY (US) | 2007-06-07 | — | — | WO | disclosed |
| US-20070122746-A1 | BENZOPYRAN COLORANTS, METHOD OF MANUFACTURE, AND METHOD OF USE | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2007-05-31 | — | — | US | disclosed |
| US-4097484-A | ORGANIC PIGMENTS, PLASTICS | CIBA-GEIGY CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |
| US-4002635-A | FOR COLORING PLASTICS AND LACQUERS | CIBA-GEIGY CORPORATION (US) | 1977-01-11 | — | — | US | disclosed |
| US-3994899-A | METHINE | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070122746-A1 | BENZOPYRAN COLORANTS, METHOD OF MANUFACTURE, AND METHOD OF USE | CBR3, CBR1, NQO1 | GRIN1 3915/4885GRIN2B 4371/4885EGFR 4288/4885 |
| US-20070238817-A1 | Articles Comprising Benzopyran Colorants, Method Of Manufacture, And Method Of Use | CBR3, CBR1, HCCS | GRIN1 4427/4885GRIN2B 4748/4885EGFR 4559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.