SCHEMBL3391983

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1349046	0.83	FPR2 (0.45)	FPR2PROKR1HTR2AHTR2CHTR7
	SCHEMBL16380668	0.83	AKT2 (0.49)	HRH3HRH4POLBCACNA2D1CACNA1B
	SCHEMBL10112214	0.83	CCR5 (0.48)	HRH3HRH4FPR2HTR2AHTR2C
	SCHEMBL3394400	0.83	HTR2A (0.64)	CACNA2D1CACNA1BCACNB1CACNA1CHTR2A
	SCHEMBL189154	0.83	HTR2A (0.46)	HRH3HRH4KMT2AHTR2AHTR2C
	SCHEMBL3392214	0.82	CARM1 (0.63)	HRH3CACNA2D1CACNA1BCACNB1CACNA1C
	SCHEMBL3391932	0.81	POLB (0.49)	HRH3HRH4POLBCACNA2D1CACNA1B
	Cyclopropane SCHEMBL6425247	0.80	DHODH (0.47)	HRH3FPR2PROKR1SLC6A2SLC6A4
	SCHEMBL10749366	0.80	DHODH (0.47)	HRH3FPR2PROKR1HTR2AHTR2C
	SCHEMBL8611840	0.80	DHODH (0.51)	HRH3FPR2PROKR1POLBSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.