SCHEMBL3394400

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1348883	0.83	HTR2A (0.58)	HTR2AHTR2CHTR7CYP2D6HTR6
	SCHEMBL3391983	0.83	HRH3 (0.55)	HTR2AHTR2CHTR7CYP2D6RPS6KB1
	SCHEMBL10112214	0.83	CCR5 (0.48)	HTR2AHTR2CHTR7CYP2D6CARM1
	SCHEMBL189154	0.83	HTR2A (0.46)	HTR2AHTR2CHTR7CYP2D6HTR6
	SCHEMBL3392214	0.82	CARM1 (0.63)	HTR2AHTR2CCYP2D6CACNA2D1CACNA1B
	SCHEMBL21381794	0.82	HTR2A (0.56)	HTR2AHTR2CHTR7CYP2D6HTR6
	SCHEMBL22957917	0.81	HTR2A (0.51)	HTR2AHTR2CHTR7CYP2D6HTR6
	SCHEMBL3051979	0.80	HTR2A (0.55)	HTR2AHTR2CHTR7CYP2D6HTR6
	SCHEMBL31489727	0.80	HTR2A (0.55)	HTR2AHTR2CHTR7CYP2D6HTR6
	SCHEMBL3393989	0.79	MEN1 (0.47)	HTR2AHTR2CHTR7CYP2D6CACNA2D1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.