Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 9/20 | 0.59 |
| ▸ | DDO | Q99489 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | FASN | P49327 | 3/20 | 0.42 |
| ▸ | PDE9A | O76083 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389922 | 0.81 | DAO (0.46) | DAODDOFASNMCL1 | |
| SCHEMBL3422279 | 0.78 | DAO (0.61) | DAODDOFASN | |
| SCHEMBL3393710 | 0.78 | DAO (0.54) | DAODDOFASNSRC | |
| SCHEMBL9389330 | 0.75 | KDM4E (0.43) | DAODDOKDM4EFASNAR | |
| SCHEMBL3363456 | 0.75 | DAO (1.00) | DAODDOKDM4EALDH1A1MAPT | |
| SCHEMBL16767849 | 0.75 | DAO (1.00) | DAODDOKDM4EALDH1A1MAPT | |
| SCHEMBL15690473 | 0.75 | DAO (0.65) | DAODDOKDM4EALDH1A1MAPT | |
| SCHEMBL3423807 | 0.75 | DAO (1.00) | DAODDOKDM4EALDH1A1MAPT | |
| SCHEMBL15506643 | 0.74 | KDM4E (0.53) | DAOKDM4EALDH1A1MAPT | |
| SCHEMBL29063172 | 0.73 | SLC9A1 (0.41) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |