Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 11/20 | 0.61 |
| ▸ | DDO | Q99489 | 5/20 | 0.45 |
| ▸ | FASN | P49327 | 3/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393710 | 0.82 | DAO (0.54) | DAODDOFASNIDH1UPP1 | |
| SCHEMBL3392115 | 0.78 | DAO (0.59) | DAODDOFASN | |
| SCHEMBL3433397 | 0.76 | DAO (0.67) | DAODDO | |
| SCHEMBL16767851 | 0.76 | DAO (1.00) | DAODDO | |
| SCHEMBL2430502 | 0.74 | MAOA (0.47) | MAOAMAOB | |
| SCHEMBL3422876 | 0.71 | DAO (0.54) | DAODDOFASN | |
| SCHEMBL2433037 | 0.71 | KDM4E (0.42) | MAOAMAOB | |
| SCHEMBL2430632 | 0.71 | MAOA (0.39) | DAOMAOAMAOB | |
| SCHEMBL9393317 | 0.71 | FASN (0.57) | DAODDOFASN | |
| SCHEMBL3395093 | 0.70 | DAO (0.67) | DAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |