Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425809 | 0.90 | KCNH2 (0.49) | KCNH2CDK4CDK2MAPK14CDC7 | |
| SCHEMBL3392059 | 0.85 | KCNH2 (0.74) | KCNH2FFAR1TGFBR1ABCB1ABCG2 | |
| SCHEMBL13425820 | 0.81 | KCNH2 (0.40) | KCNH2CDK4CDK2MAPK14 | |
| SCHEMBL3392275 | 0.78 | KCNH2 (0.46) | KCNH2FFAR1METAP2METAP1TGFBR1 | |
| SCHEMBL13425764 | 0.78 | KCNH2 (0.53) | KCNH2CDK4CDK2CDC7KIT | |
| SCHEMBL13426284 | 0.78 | KCNH2 (0.59) | KCNH2TGFBR1MAPK14LRRK2ABCB1 | |
| SCHEMBL3395596 | 0.77 | KCNH2 (0.40) | KCNH2FFAR1METAP2METAP1TGFBR1 | |
| SCHEMBL3393337 | 0.76 | KCNH2 (0.58) | KCNH2TGFBR1ABCB1ABCG2CHEK1 | |
| SCHEMBL13426043 | 0.76 | KCNH2 (0.43) | KCNH2CHEK1 | |
| SCHEMBL13425594 | 0.75 | KCNH2 (0.38) | KCNH2FFAR1METAP2METAP1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |