Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 2/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | GPR39 | O43194 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425594 | 0.87 | KCNH2 (0.38) | KCNH2METAP2METAP1VNN1TGFBR1 | |
| SCHEMBL3393337 | 0.81 | KCNH2 (0.58) | KCNH2PDE5AGRM5TGFBR1CHEK1 | |
| SCHEMBL13426263 | 0.79 | KCNH2 (0.39) | KCNH2PDE5AEGLN1 | |
| SCHEMBL3395600 | 0.79 | L3MBTL1 (0.35) | KCNH2METAP2METAP1GRM5TGFBR1 | |
| SCHEMBL3392272 | 0.77 | KCNH2 (0.54) | KCNH2PDE5AMETAP2METAP1TGFBR1 | |
| SCHEMBL13426043 | 0.77 | KCNH2 (0.43) | KCNH2CHEK1 | |
| SCHEMBL13425706 | 0.75 | EGFR (0.36) | CHEK1 | |
| SCHEMBL13425781 | 0.75 | GABRG2 (0.38) | KCNH2 | |
| SCHEMBL13425685 | 0.74 | MAPT (0.41) | MAPK14 | |
| SCHEMBL13425783 | 0.73 | KCNH2 (0.40) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |